2023
DOI: 10.2217/epi-2023-0322
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Decoding Mitochondrial–Nuclear (epi)genome Interactions: The Emerging Role of ncRNAs

Julia Nguyen,
Quinn Le,
Phyo W Win
et al.

Abstract: Bidirectional communication between the mitochondria and the nucleus is required for several physiological processes, and the nuclear epigenome is a key mediator of this relationship. ncRNAs are an emerging area of discussion for their roles in cellular function and regulation. In this review, we highlight the role of mitochondrial-encoded ncRNAs as mediators of communication between the mitochondria and the nuclear genome. We focus primarily on retrograde signaling, a process in which the mitochondrion relays… Show more

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