Decoding visceral adipose tissue molecular signatures in obesity and insulin resistance: a multi‐omics approach
Dipayan Roy,
Raghumoy Ghosh,
Ritwik Ghosh
et al.
Abstract:ObjectiveObesity‐associated insulin resistance (IR) is responsible for considerable morbidity and mortality globally. Despite vast genomic data, many areas, from pathogenesis to management, still have significant knowledge gaps. We aimed to characterize visceral adipose tissue (VAT) in obesity and IR through a multi‐omics approach.MethodsWe procured data on VAT samples from the Gene Expression Omnibus (GEO) for the following two groups: 1) populations with obesity (n = 34) versus those without (n = 26); and 2)… Show more
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