Decontamination Methods for Respiratory Protection Mask Model N95: A Rapid Review

Abstract

<jats:title>Abstract</jats:title> <jats:p><jats:bold>Background:</jats:bold> N95 respiratory protection masks are used by healthcare professionals to prevent contamination with infectious microorganisms transmitted by droplets or aerosols. <jats:bold>Methods: </jats:bold>We conducted a rapid review of the literature analyzing the effectiveness of decontamination methods for mask reuse. The review was carried out in April 2020 using a simplification of the formal systematic review process. A total of 166 articles were retrieved of which 17 laboratory-based studies were selected. <jats:bold>Results:</jats:bold> Two of the studies only examined the effectiveness of decontamination methods, seven only reported on the maintenance of mask integrity, and eight considered both outcomes. Twelve decontamination methods were included in the studies. <jats:bold>Conclusions: </jats:bold>Positive results should be considered with caution as they represent a small number of studies, reflect ideal laboratory conditions, and may have limited applicability in realistic situations and for health systems. Nonetheless, five methods appear promising: hydrogen peroxide vapor, ultraviolet irradiation, dry heat, wet heat/pasteurization, and microwave ovens.</jats:p>