Decreased Th1 Cells and Increased Th2 Cells In Peripheral Blood Are Associated with Idiopathic Inflammatory Myopathies Patients With Interstitial Lung Disease
Abstract:Objective.
Interstitial lung disease (ILD) is a common and highly fatal manifestation of idiopathic inflammatory myopathies (IIMs). T helper (Th) cells play important roles in the initiation of ILD. Here, we investigated the clinical significance of peripheral blood Th cells in IIMs-ILD patients.
Methods.
11 healthy controls (HC) and 57 patients diagnosed with IIMs were included, including 30 with ILD (IIMs-ILD) and 23 without ILD (IIMs-non-ILD). Circulating Th1, Th2, Th17, and Treg cells were examined by fl… Show more
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