Abstract:Deep brain stimulation (DBS) is an effective surgical treatment in ameliorating symptoms of Parkinson's disease (PD), dystonia and tremor. DBS involves the surgical insertion of electrode(s) to stimulate either the subthalamic nucleus, globus pallidum interna or ventral intermediate nucleus of the thalamus, depending on the condition being treated. These structures play a critical role in the relay of electrical signals within the basal ganglia to facilitate movement. The mechanism by which DBS improves sympto… Show more
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