Deep Brain Stimulation as an Alternative Treatment for Alzheimer's Disease

Abstract

Aim: To describe through a literature review Alzheimer's disease and a new complementary therapy that allows an improvement in the individual's quality of life. Methodology: A bibliographic search was performed in the main health databases PUBMED and BVS Regional Portal, in which different studies, including laboratory studies, case reports, systematic reviews, narratives, and reviews, which were developed in living individuals, were included. Therefore, articles that did not address the topic in question, letters to the editor, opinion articles, duplicate literature in databases, and literature that did not address the variables under study were excluded. Results: According to the methodological analysis, it is observed that the average publication of articles in the Pubmed database was 2.33 and with a standard deviation of 1.11. While in BVS Regional Portal, the average was 1.0 and the standard deviation was 0.71. Thus, it is possible to verify that there was a significant variation in the number of articles in the two databases. Conclusion: It is concluded that deep brain stimulation applied to the fornix is a safe procedure, in addition to being a very promising alternative for patients who are refractory to other treatments. Therefore, there is a high benefit and safety in the use of the f-DPE technique in patients with AD.