In recent years, with the increase of computer computing power, Deep Learning has begun to be favored. Its learning of non-linear feature combinations has played a role that traditional machine learning cannot reach in almost every field. The application of Deep Learning has also driven the advancement of Factorization Machine (FM) in the field of recommendation systems, because Deep Learning and FM can learn high-order and low-order features combinations respectively, and FM's hidden vector system enables it to learn information from sparse data. The integration of them has attracted the attention of many scholars. They have researched many classic models such as Factorization-supported Neural Network (FNN), Product-based Neural Networks (PNN), Inner PNN (IPNN), Wide&Deep, Deep&Cross, DeepFM, etc. for the Click-Through-Rate (CTR) problem, and their performance is getting better and better. This kind of model is also suitable for agriculture, meteorology, disease prediction and other fields due to the above advantages. Based on the DeepFM model, we predicts the incidence of hepatitis in each sample in the structured disease prediction data of the 2020 Artificial Intelligence Challenge Preliminary Competition, and make minor improvements and parameter adjustments to DeepFM. Compared with other models, the improved DeepFM has excellent performance in AUC. This research can be applied to electronic medical records to reduce the workload of doctors and make doctors focus on the samples with higher predicted incidence rates. For some changing data, such as blood pressure, height, weight, cholesterol, etc., we can introduce the Internet of Medical Things (IoMT). IoMT's sensors can be used to conduct transmission to ensure that the disease can be predicted in time, just in case. After joining IoMT, a healthcare system is formed, which is superior in forecasting and time performance.