Deep Mycoses in Amazon Region

Talhari, Sinésio; Cunha, Maria da Graça Souza; Schettini, Antônio Pedro Mendes; Talhari, Anette C.

doi:10.1111/j.1365-4362.1988.tb00925.x

Cited by 28 publications

(29 citation statements)

References 2 publications

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“…In the other regions, there have been only sporadic reports 14 . An epidemiological survey carried out in the county of Sidrolândia, located 60 km from Campo Grande, the capital of the Mato Grosso do Sul State, found a 9.7% rate of reactivity to histoplasmin 1 , suggesting an area of low endemicity.…”

Section: Discussionmentioning

confidence: 99%

Study of 30 cases of histoplasmosis observed in the Mato Grosso do Sul State, Brazil

Chang

Taira

Paniago

et al. 2007

Rev. Inst. Med. trop. S. Paulo

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Thirty cases of histoplasmosis observed at the University Hospital of the Federal University of Mato Grosso do Sul (HU-UFMS) from January 1998 to December 2005 are reported. Most (83.3%) of the patients were men, average 33.4 years old, 63.3% of them were born and living in Mato Grosso do Sul and 83.3% presented AIDS as an underlying disease. In almost all cases (96.7%) the disease occurred in its disseminated form and the most frequent clinical manifestations were: fever (83.3%), weight loss (70.0%), cough (63.3%), hepatomegaly and splenomegaly (40.0%), and lymph node enlargement (36.7%). The laboratory diagnosis was obtained in 29 patients by isolation of Histoplasma capsulatum from various clinical specimens cultivated in Sabouraud dextrose and brain heart infusion agar and in 16 patients the fungus was observed by direct microscopy of Giemsa-stained smears. The observed mortality was 40%. This is the first report in the literature of the occurrence of histoplasmosis in Mato Grosso do Sul State.

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Section: Discussionmentioning

confidence: 99%

Study of 30 cases of histoplasmosis observed in the Mato Grosso do Sul State, Brazil

Chang

Taira

Paniago

et al. 2007

Rev. Inst. Med. trop. S. Paulo

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“…Some authors proposed 2 polar groups: hyperergic (macules and gummas) and hypoergic (keloid-like). Although internal organ involvement is rare, there is the case of a patient from Costa Rica who presented testicular involvement and secondary lymphangitis after 47 years of the disease [13].…”

Section: Discussionmentioning

confidence: 99%

Disseminated infection with Lacazia loboi and immunopathology of the lesional spectrum

Carneiro¹,

Fischer²,

Brandão³

et al. 2015

Human Pathology

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“…1,3,5 The human disease appears to be endemic in Central and Western Brazil, Bolivia, Colombia, Costa Rica, Ecuador, Guyana, Mexico, Panama, Peru, Suriname and Venezuela. [1][2][3][4][5][6]8,11,13,21 However, there have been isolated cases in the United States, 22 Canada, 16 Africa, 23 the Netherlands, 24 France 25 and Germany. 15 More than 550 human cases have been reported to date, especially in patients with a history of travel or residence in the areas of endemicity or in communities along rivers.…”

Section: 241819mentioning

confidence: 99%

Lobomycosis: A case from Southeastern Europe and review of the literature

Papadavid¹,

Dalamaga²,

Kapniari³

et al. 2012

J Dermatol Case Rep

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Background: Lobomycosis, also known as Jorge Lobo's disease, represents a rare chronic subcutaneous mycosis caused by the fungus Lacazia loboi, an organism that is found within lesions but has not been cultured to date. The natural reservoir of L. loboi is unknown but it is believed to be aquatic, or associated with soil and vegetation. More than 550 human cases have been reported, especially in patients with a history of travel or residence in endemic areas (Central and South America, particularly Brazil) or in communities along rivers. Main observations:We describe a 64-year-old Greek female farmer living in a coastal region, who presented with an erythematous plaque on her left inner thigh resembling a keloid. The diagnosis was based on the triad: 1) absence of fungal growth in cultures, 2) positive direct microscopic examination of the lesion and 3) histopathology, all consistent with lobomycosis. Particularly, skin biopsy showed deep cutaneous fungal infection with granulomatous reaction. Fungal cells were found inside giant cells. The fungi were thick-walled with some budding, isolated or in short chains. Dermal fibrosis was present. Our patient had a medical history of common variable immunodeficiency but no history of travel to South or Central America. She probably acquired this rare infection by injury during her agricultural works. Conclusion:Our case represents probably the first documented case of human lobomycosis in Southeastern Europe. This case is unusual due to the rarity of lobomycosis in Mediterranean countries, particularly in Southeastern Europe. (J Dermatol Case Rep. 2012; 6(3): 65-69)

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Deep Mycoses in Amazon Region

Cited by 28 publications

References 2 publications

Study of 30 cases of histoplasmosis observed in the Mato Grosso do Sul State, Brazil

Study of 30 cases of histoplasmosis observed in the Mato Grosso do Sul State, Brazil

Disseminated infection with Lacazia loboi and immunopathology of the lesional spectrum

Lobomycosis: A case from Southeastern Europe and review of the literature

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