Deep-Red Emissive Fluorescent Probe for Sensitive Detection of Cysteine in Milk and Living Cells

Hao, Yuanqiang; Zhang, Yintang; Luo, Lijie; Zhu, Dandan; Xu, Maotian; Zeng, Rongjin; Chen, Shu

doi:10.1007/s12161-022-02280-9

Cited by 8 publications

(3 citation statements)

References 67 publications

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“…It is also used to produce preservatives and antioxidants to improve product stability and shelf life. Given their high reactivity and potential toxicity, industrial emissions of thiophenols can contaminate water bodies and the atmosphere, making it essential to monitor their concentrations for environmental protection and health safety [ 213 , 214 , 215 ]. The development of photoswitchable probes has provided effective tools for detecting these small thiol molecules [ 216 , 217 ].…”

Section: Applications Of Photoswitchable Fluorescent and Colorimetric...mentioning

confidence: 99%

Recent Advances in Photoswitchable Fluorescent and Colorimetric Probes

Chen,

Tang,

Yang

et al. 2024

Molecules

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In recent years, significant advancements have been made in the research of photoswitchable probes. These probes undergo reversible structural and electronic changes upon light exposure, thus exhibiting vast potential in molecular detection, biological imaging, material science, and information storage. Through precisely engineered molecular structures, the photoswitchable probes can toggle between “on” and “off” states at specific wavelengths, enabling highly sensitive and selective detection of targeted analytes. This review systematically presents photoswitchable fluorescent and colorimetric probes built on various molecular photoswitches, primarily focusing on the types involving photoswitching in their detection and/or signal response processes. It begins with an analysis of various molecular photoswitches, including their photophysical properties, photoisomerization and photochromic mechanisms, and fundamental design concepts for constructing photoswitchable probes. The article then elaborates on the applications of these probes in detecting diverse targets, including cations, anions, small molecules, and biomacromolecules. Finally, it offers perspectives on the current state and future development of photoswitchable probes. This review aims to provide a clear introduction for researchers in the field and guidance for the design and application of new, efficient fluorescent and colorimetric probes.

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Section: Applications Of Photoswitchable Fluorescent and Colorimetric...mentioning

confidence: 99%

Recent Advances in Photoswitchable Fluorescent and Colorimetric Probes

Chen,

Tang,

Yang

et al. 2024

Molecules

Self Cite

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“…Thiols, including cysteine, homocysteine, cysteinylglycine, and glutathione (GSH), hold crucial roles in cellular functions [99][100][101][102]. Detecting these compounds is vital for diagnosing metabolic disorders and diseases like diabetes and leukemia [103][104][105].…”

Section: Biothiolsmentioning

confidence: 99%

Chemiluminescence‐driven photoelectrochemical sensor: A mini review

Luo,

Hao,

Zhang

et al. 2023

Electroanalysis

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“…In recent years, remarkable progress has been made in the construction of biothiol fluorescent probes [4,[17][18][19]. Many reported fluorescent probes can be responded to biothiols in cells, tissues, and a variety of amino acids.…”

Section: Introductionmentioning

confidence: 99%

Theoretical Investigation of a Coumarin Fluorescent Probe for Distinguishing the Detection of Small-Molecule Biothiols

Deng,

Huang,

Feng

et al. 2024

Molecules

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Monitoring the level of biothiols in organisms would be beneficial for health inspections. Recently, 3-(2′-nitro vinyl)-4-phenylselenyl coumarin as a fluorescent probe for distinguishing the detection of the small-molecule biothiols cysteine/homocysteine (Cys/Hcy) and glutathione (GSH) was developed. By introducing 4-phenyselenium as the active site, the probe CouSeNO2/CouSNO2 was capable of detecting Cys/Hcy and GSH in dual fluorescence channels. Theoretical insights into the fluorescence sensing mechanism of the probe were provided in this work. The details of the electron excitation process in the probe and sensing products under optical excitation and the fluorescent character were analyzed using the quantum mechanical method. All these theoretical results would provide insight and pave the way for the molecular design of fluorescent probes for the detection of biothiols.

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Deep-Red Emissive Fluorescent Probe for Sensitive Detection of Cysteine in Milk and Living Cells

Cited by 8 publications

References 67 publications

Recent Advances in Photoswitchable Fluorescent and Colorimetric Probes

Recent Advances in Photoswitchable Fluorescent and Colorimetric Probes

Chemiluminescence‐driven photoelectrochemical sensor: A mini review

Theoretical Investigation of a Coumarin Fluorescent Probe for Distinguishing the Detection of Small-Molecule Biothiols

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