Deep skin and soft tissue infection of the neck – first sign of unrecognized diabetes mellitus

Wollina, Uwe; Bujok, Violetta; Fürll, Caroline; Hansel, Gesina

doi:10.7241/ourd.20203.21

Our Dermatol Online

2020

DOI: 10.7241/ourd.20203.21

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Deep skin and soft tissue infection of the neck – first sign of unrecognized diabetes mellitus

Uwe Wollina¹,

Violetta Bujok²,

Caroline Fürll³

et al.

Abstract: Figure 1: Carbuncle of the neck with putride discharge. The erythema and swelling in the surrounding tissue indicate deep skin and soft tissue infection more extensive than the initial carbuncle.

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2024

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Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers

Jamshidnejad-Tosaramandani,

Kashanian,

Omidfar

et al. 2024

Front. Bioeng. Biotechnol.

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Diabetes mellitus (DM) is a prevalent disorder with an urgent need for continuous, precise, and on-site biomarker monitoring devices. The continuous monitoring of DM biomarkers from different biological matrices will become routine in the future, thanks to the promising biosensor design. Lately, employing different nanomaterials in biosensor receptor parts has had a great impact on smart DM monitoring. Among them, gold nanostructures (AuNSs) have arisen as highly potential materials in fabricating precise DM biosensors due to their unique properties. The present study provides an update on the applications of AuNSs in biosensors for detecting glucose as well as other DM biomarkers, such as glycated hemoglobin (HbA1c), glycated albumin (GA), insulin, insulin antibodies, uric acid, lactate, and glutamic acid decarboxylase antibodies (GADA), with a focus on the most important factors in biosensor performance such as sensitivity, selectivity, response time, and stability. Specified values of limit of detection (LOD), linear concentrations, reproducibility%, recovery%, and assay time were used to compare studies. In conclusion, AuNSs, owing to the wide electrochemical potential window and low electrical resistivity, are valuable tools in biosensor design, alongside other biological reagents and/or nanomaterials.

show abstract

Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers

Jamshidnejad-Tosaramandani,

Kashanian,

Omidfar

et al. 2024

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

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Deep skin and soft tissue infection of the neck – first sign of unrecognized diabetes mellitus

Abstract: Figure 1: Carbuncle of the neck with putride discharge. The erythema and swelling in the surrounding tissue indicate deep skin and soft tissue infection more extensive than the initial carbuncle.

Cited by 1 publication

References 8 publications

Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers

Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers

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