Deep vein thrombosis and prostatectomy

Arsdalen, Keith N. Van; Smith, Michael Sharwood; Barnes, Robert W.; Koontz, Warren W.; Clarke, G. H.

doi:10.1016/0090-4295(83)90040-7

Cited by 28 publications

(15 citation statements)

References 18 publications

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“…[25][26][27][28]31,32 We identified 11 studies in these reviews that fulfilled our inclusion criteria and measured outcomes relevant to this context. 37,[94][95][96][97][98][99][100][101][102][103] Our systematic search of RCTs did not identify any additional study that fulfilled the inclusion criteria.…”

Section: Recommendationmentioning

confidence: 99%

“…94,96,97,101,102 Eight studies reported the effect on the development of symptomatic PEs, 37,[95][96][97][98][99]102,103 and 4 studies reported the effect on any PE. 94,100,101,103 One study reported data on symptomatic proximal and symptomatic distal DVTs, 98 whereas 6 studies reported on any proximal DVT, 37,94,96,[98][99][100] and 5 studies reported on any distal DVT. 37,94,96,98,100 The EtD framework is available online at https://guidelines.gradepro.org/profile/1584FD2F-9CC6-9C59-8DF5-48F0045F1BE5.…”

Section: Recommendationmentioning

confidence: 99%

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American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

et al. 2019

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Background:Venous thromboembolism (VTE) is a common source of perioperative morbidity and mortality.Objective:These evidence-based guidelines from the American Society of Hematology (ASH) intend to support decision making about preventing VTE in patients undergoing surgery.Methods:ASH formed a multidisciplinary guideline panel balanced to minimize bias from conflicts of interest. The McMaster University GRADE Centre supported the guideline-development process, including performing systematic reviews. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess evidence and make recommendations, which were subject to public comment.Results:The panel agreed on 30 recommendations, including for major surgery in general (n = 8), orthopedic surgery (n = 7), major general surgery (n = 3), major neurosurgical procedures (n = 2), urological surgery (n = 4), cardiac surgery and major vascular surgery (n = 2), major trauma (n = 2), and major gynecological surgery (n = 2).Conclusions:For patients undergoing major surgery in general, the panel made conditional recommendations for mechanical prophylaxis over no prophylaxis, for pneumatic compression prophylaxis over graduated compression stockings, and against inferior vena cava filters. In patients undergoing total hip or total knee arthroplasty, conditional recommendations included using either aspirin or anticoagulants, as well as for a direct oral anticoagulant over low-molecular-weight heparin (LMWH). For major general surgery, the panel suggested pharmacological prophylaxis over no prophylaxis, using LMWH or unfractionated heparin. For major neurosurgery, transurethral resection of the prostate, or radical prostatectomy, the panel suggested against pharmacological prophylaxis. For major trauma surgery or major gynecological surgery, the panel suggested pharmacological prophylaxis over no prophylaxis.

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Section: Recommendationmentioning

confidence: 99%

Section: Recommendationmentioning

confidence: 99%

American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

et al. 2019

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“…The reported incidence of DVT after TURP is 6.8–10%, while PE 0.2–2.2% before prophylaxis was commonly used. [5,6] There are few researches comparing the incidence of postoperative thromboembolic events between TURP and HoLEP. The reason may be that the incidence of thromboembolic events after TURP or HoLEP is much lower than that of open prostatectomy, [7] the misdiagnosis of postoperative DVT is high and most fatal PE can only be confirmed by autopsy.…”

Section: Introductionmentioning

confidence: 99%

Transurethral resection versus holmium laser enucleation of the prostate

Bai

Feng

et al. 2019

Medicine

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Objectives: The purpose of this study was to compare transurethral resection of the prostate (TURP) versus holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic hyperplasia (BPH) focusing on perioperative thrombin generation and fibrinolysis. Methods: Sixty-five BPH patients were prospectively randomly assigned to undergo TURP (n = 32) or HoLEP (n = 33). The prothrombin fragment (PF) 1+2, thrombin-antithrombin complex (TAT), tissue plasminogen activator (t-PA), and plasminogen activator inhibitor-1 (PAI-1) were measured preoperatively, at the 1st day and 3rd day after surgery. Results: PF1+2, TAT, t-PA, and PAI-1 significantly elevated at day 1 and day 3 after surgery ( P < .05) and remarkedly decreased from the 1st day to the 3rd day ( P < .05). The levels of PF1+2 and TAT were higher in TURP group postoperatively than that in HoLEP group ( P < .05). There is no significant difference between 2 groups in regard of t-PA and PAI-1 ( P > .05). Conclusion: The activation of thrombin generation and fibrinolysis system were noticed in BPH patients after TURP or HoLEP. TURP may associate with a higher hypercoagulable thrombotic risk than HoLEP.

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“…The recorded incidence of deep venous thrombosis following transurethral resection of the prostate (TURP) varies between 6.8 and 10% using the radioactive fibrinogen uptake test (Hedlung, 1975 ;Arsdalen et al, 1983). Fatal pulmonary embolus following TURP is uncommon, with an incidence of 0.3 to 2.2% (Antila et al, 1966;Valk et al, 1975).…”

mentioning

confidence: 99%

Prophylactic Subcutaneous Heparin does not Increase Operative Blood Loss in Transurethral Resection of the Prostate

Wilson¹,

Smith²,

Paton³

et al. 1988

British Journal of Urology

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A prospective randomised study of subcutaneous heparin compared with no heparin was performed in 60 patients undergoing transurethral resection of the prostate. Operative blood loss in the irrigation fluid was measured using a haemoglobinometer. Blood loss correlated with the amount of prostate resected and the duration of the procedure. Subcutaneous heparin had no significant effect on the measured blood loss in transurethral resection of the prostate and can be used as a safe means of prophylaxis against thrombo-embolic complications.

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Deep vein thrombosis and prostatectomy

Cited by 28 publications

References 18 publications

American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

Transurethral resection versus holmium laser enucleation of the prostate

Prophylactic Subcutaneous Heparin does not Increase Operative Blood Loss in Transurethral Resection of the Prostate

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