Deep Vein Thrombosis in Elderly Patients following Surgery for Fracture of the Proximal Femur

Magetsari, Rahadyan; Dewo, Punto; Nugroho, AS; Lanodiyu, Zikrina Abyanti

doi:10.5704/moj.1411.002

Cited by 20 publications

(10 citation statements)

References 18 publications

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“…In previously published literature, the distribution of DVT in lower extremity fractures was studied. Some authors concluded that hip fractures presented with a highest incidence of 17-58% 6 , the incidence in distal femur fractures treated surgically was 25% 7 , and in foot and ankle surgery was 2.1%. 3 It seems that DVT may occur more often in the proximal fracture of lower extremity, and we speculate that fracture site may be correlated closely with the incidence of DVT in lower extremities.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Chen

Wang

et al. 2018

Pak J Med Sci

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Objective:To clarify if fracture site is correlated to the occurrence of deep venous thrombosis, and determine the risk factors of deep venous thrombosis in lower extremity fractures, help surgeons make prophylaxis for the disease correctly.Methods:The patients with lower extremity fractures treated surgically in the orthopedics department of our hospital from May 2012 to July 2017 were reviewed retrospectively. The clinical data including age, gender, fracture site, surgery modality, hospital stay, operation time, occupation type, hypertension, coronary heart disease, diabetes, smoking status, drinking status, postoperative exercises were collected and analyzed.Results:Eight hundred and twenty-nine patients were included for analysis, in which 68 were included in deep venous thrombosis group, 761 were included in the non-deep venous thrombosis group, and the incidence of deep venous thrombosis was 8.2%. There were significant differences in age, fracture site, surgery modality, occupation type, operation time, smoking status, hospital stay and postoperative exercises between the two groups (p<0.05), but no significant differences in gender, drinking status, coronary heart disease, diabetes and hypertension (p>0.05). In multivariate analysis, old age greater than 50 years, arthroplasty and operation time more than three hours were independent risk factors, while physical labor and postoperative exercises were protective factors for deep venous thrombosis in lower extremity fractures.Conclusion:Fracture site was correlated to the incidence of deep venous thrombosis, old age, longer operation time, and arthroplasty were independent risk factors, physical labor and postoperative exercises were protective factors for deep venous thrombosis in patients with lower extremity fractures.

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Section: Introductionmentioning

confidence: 99%

Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Chen

Wang

et al. 2018

Pak J Med Sci

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“…On the other hand, another study on elderly patients reported that the prevalence of asymptomatic DVT on admission and the incidence during hospital follow up were respectively 5.5% and 2.6 per 1,000 person-days, the prevalence and the incidence reached respectively 17.8% and 6.0 per 1,000 person-days among patients over 80 years ( 11 ). Also, a study in Indonesia ( 12 ) reported (42.86 %) as prevalence of DVT among elderly patients. According to the results of our study, no significant association was observed between gender and the development of DVT among elderlies.…”

Section: Discussionmentioning

confidence: 96%

Deep venous thrombosis in elderly patients as a surgical emergency at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

Alanazi

Alenezi

et al. 2017

Electron Physician

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BackgroundDeep venous thrombosis (DVT) is a condition that occurs frequently among surgical, as well as acutely ill hospitalized medical patients, and is responsible for significant morbidity and mortality in hospitalized patients. Risk factors include older age, surgery and immobilization (as with bed rest, orthopedic casts, and sitting on long flights.ObjectiveThis study was conducted to identify the frequency and factors associated with occurrence of DVT among elderly patients referred to King Abdulaziz University (KAU) Hospital, Jeddah, Kingdom of Saudi Arabia.MethodsThe current study is a hospital based cross sectional study. The emergency, inpatients and outpatients’ departments at KAU hospital were reviewed. We studied all the referred elderly subjects during the study period. All elderly patients (540) referred to or admitted to the hospital departments and who were clinically suspected to have DVT and subjected to Doppler examination were included in the study. Data were analyzed using descriptive statistics and Chi square test.ResultsBased on the results of Doppler examination, DVT was detected in 97 (18.0%) of the studied elderly population. There were no significant differences in gender between patients who developed DVT and those who were negative by Doppler examination (p=0.018). Other comorbidities as diabetes, IHD and hypertension were significantly associated with the occurrence of DVT among the participants (p=0.05, 0.05 and 0.04 respectively). Furthermore, the other investigated factors such as being bed ridden, cancer, orthopedic cast and previous DVT were not significantly associated with the development of DVT among the studied elderly patients (p=0.42, 0.16, 0.45 and 0.75 respectively).ConclusionDVT has high prevalence in Jeddah; KSA. Thrombophilia screening should be regular for elderly patients with diabetes, hypertension and bed-ridden patients with recurrent DVT or patients with other risk factors. Knowing the most common risk factors and their significance in developing DVT is essential for early detection of DVT to prevent unwanted complications for elderlies.

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“…Our results showed that D-dimer levels above 0.5 ug/ml at admission were associated with a 47% increased risk of DVT, which was comparable to the ndings of Zhang et al [10] study of lower extremity fractures. D-dimer is a brin degradation marker that represents secondary brinolytic activity, hypercoagulability, and brinolytic activity in the blood, which has clinical value in the diagnosis of thrombus events [27]. Yamasaki et al [28] retrospectively collected 588 patients undergoing lumbar spine surgery and found that the risk of DVT increased by 9% with D-dimer greater than 19.2 ug/ml one week after surgery.…”

Section: Discussionmentioning

confidence: 99%

Preoperative incidence and risk factors of deep vein thrombosis in patients with an isolated patella fracture

Yang

Wei

Wang

et al. 2021

Preprint

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Background The purpose of this study was to investigate the incidence, location, and related factors of preoperative deep venous thrombosis (DVT) in patients with isolated patellar fractures. Methods Patients with an isolated patellar fracture, admitted between January 2013 and December 2019 at our institution, were retrospectively analyzed. Upon admission, patients underwent routine Doppler ultrasound scanning (DUS) of the bilateral lower extremities to detect DVT; those with DVT were assigned to the case group and those without DVT to the control group. Data on demographics, comorbidities, and laboratory test results upon admission were extracted. Differences between the two groups were evaluated using univariate analyses, and independent risk factors associated with DVT were identified by logistic regression analysis. Results During the study window, 827 patients were included, of whom 5.8% (48/827) were found to have preoperative DVT. Among those with DVT, 85.4% (41/48), 8.3 % (4/48), and 6.3% (3/48) occurred in the injured, non-injured, and bilateral lower extremities, respectively. Multivariate analysis showed that age (each increase of 1 year) (odds ratio, OR = 1.02), residential area (OR = 5.00), delay of injury to DUS (in each day, OR = 1.33), and elevated plasma D-dimer level (> 0.5 µg/mL, OR = 2.47) were independent risk factors associated with DVT. Conclusions Despite the low prevalence of DVT after an isolated patellar fracture, this study underscores the importance of identifying those with a high risk of DVT, especially those with multiple identifiable factors, as well as the early targeted use of thromboembolic agents, to reduce DVT occurrence.

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Deep Vein Thrombosis in Elderly Patients following Surgery for Fracture of the Proximal Femur

Cited by 20 publications

References 18 publications

Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Deep venous thrombosis in elderly patients as a surgical emergency at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

Preoperative incidence and risk factors of deep vein thrombosis in patients with an isolated patella fracture

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