Abstract:The immunologic alterations in patients on hemodialysis are only partially understood. We studied the Concanavalin A (Con A) induced suppressor cell activity of irradiated and nonirradiated cells in a mixed lymphocyte culture. Peripheral blood lymphocytes from 18 normal individuals and 14 patients on regular hemodialysis were incubated with two different concentrations of Con A (10 µg and 40 µg of Con A/million cells). Irradiated and nonirradiated cells were then tested for their capacity to suppress a standar… Show more
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