Defense status in larval stage of red palm weevil Rhynchophorus ferrugineus (Olivier) (Coleoptera: Curculionidae)

Mohamed, M. I.; Ghazy, Abdel-Hady M.; Karim, Ghada S.A. Abdel; El-Khonezy, Mohamed I.; Abdelaziz, Ahmed; Ghanem, Manal M.E.

doi:10.1016/j.bcab.2022.102465

Cited by 4 publications

(5 citation statements)

References 67 publications

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“…Knutelski et al [18] identified the bactericidal proteins and peptides (AMPs) in R. ferrugineus larval hemolymph, which showed attacin-B, cecropin, defensin, pheromone-and odorant-binding proteins, and one hypothetical AMPs. R. ferrugineus larval hemolymph is also rich in enzymes, and some of them are antioxidant enzymes like PPO and PO [36] that may aid in the hemolymph's antimicrobial activity. Lipases, transaminases such as glutamic oxaloacetic transaminase and glutamine pyruvic transaminase, acid phosphatase, and alkaline phosphatase and acetylcholinesterase, among others [32,36,37] are also present in the hemolymph.…”

Section: Composition Of R Ferrugineus Larvaementioning

confidence: 99%

“…R. ferrugineus larval hemolymph is also rich in enzymes, and some of them are antioxidant enzymes like PPO and PO [36] that may aid in the hemolymph's antimicrobial activity. Lipases, transaminases such as glutamic oxaloacetic transaminase and glutamine pyruvic transaminase, acid phosphatase, and alkaline phosphatase and acetylcholinesterase, among others [32,36,37] are also present in the hemolymph. Amino acids are also important components of the R. ferrugineus larval hemolymph, and arginine, histidine, aspartic acid, threonine, tyrosine, alanine, valine, leucine, glutamic phenylalanine, lysine, proline, glycine, methionine, and isoleucine have been identified by Abdel-Razek et al [33].…”

Section: Composition Of R Ferrugineus Larvaementioning

confidence: 99%

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Rhynchophorus ferrugineus larvae: A novel source for combating broad-spectrum bacterial and fungal infections

Niod,

Kepel,

Hessel

et al. 2024

Vet World

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Antimicrobial resistance is a growing concern due to the growth of antibiotic-resistant microorganisms, which makes it difficult to treat infection. Due to its broad-spectrum antimicrobial properties against a diverse array of bacteria, both Gram-positive and Gram-negative bacteria, and fungi, Rhynchophorus ferrugineus larval antimicrobial peptides (AMPs) have demonstrated potential as antimicrobial agents for the treatment of microbial infections and prevention of antibiotic resistance. This study emphasizes the unexplored mechanisms of action of R. ferrugineus larvae against microorganisms. Among the most widely discussed mechanisms is the effect of AMPs in larvae in response to a threat or infection. Modulation of immune-related genes in the intestine and phagocytic capacity of its hemocytes may also affect the antimicrobial activity of R. ferrugineus larvae, with an increase in phenoloxidase activity possibly correlated with microbial clearance and survival rates of larvae. The safety and toxicity of R. ferrugineus larvae extracts, as well as their long-term efficacy, are also addressed in this paper. The implications of future research are explored in this paper, and it is certain that R. ferrugineus larvae have the potential to be developed as a broad-spectrum antimicrobial agent with proper investigation. Keywords: antimicrobial, broad-spectrum, larvae, Rhynchophorus ferrugineus.

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Section: Composition Of R Ferrugineus Larvaementioning

confidence: 99%

Section: Composition Of R Ferrugineus Larvaementioning

confidence: 99%

Rhynchophorus ferrugineus larvae: A novel source for combating broad-spectrum bacterial and fungal infections

Niod,

Kepel,

Hessel

et al. 2024

Vet World

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“…In addition, the high activity of antioxidant enzymes ( Table 1 ), such as catalase [ 61 ], polyphenols oxidase and peroxidase, involved in insect defense mechanisms were also detected and analyzed in the gut of RPW [ 62 ]. Antioxidant enzymes in insects are enzymes that can balance potentially harmful reactive oxygen species (ROS).…”

Section: Protein Profile Of Rpw’s Gutmentioning

confidence: 99%

“…Catalase (EC: 1.11.1.6) and peroxidase (EC: 1.11.1.7) function to catalyze the conversion of potentially toxic hydrogen peroxide into oxygen molecules and water [ 64 ]. Polyphenol oxidase (EC: 1.14.18.1) is an enzyme that uses oxygen to catalyze the oxidation of a wide range of phenolic compounds resulting from several factors, such as exposure to insecticides and starvation [ 62 ]. The functions of the antioxidant enzymes found in the gut of RPW showed that each of the enzymes could be targeted to control the pest.…”

Section: Protein Profile Of Rpw’s Gutmentioning

confidence: 99%

“…There have been several reports stating the discovery of detoxifying genes ( Table 2 ) in RPW’s gut. Cytochrome P450 (CYP450) and glutathione-S-transferase (GST) were reported to be highly expressed in the mid-gut of RPW [ 62 , 75 , 77 , 78 ]. The detoxification system of insects consists of three phases: biotransforming, metabolizing and excreting.…”

Section: Rpw’s Gut Transcriptome Analysismentioning

confidence: 99%

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A Review on Digestive System of Rhynchophorus ferrugineus as Potential Target to Develop Control Strategies

Seman-Kamarulzaman,

Pariamiskal,

Azidi

et al. 2023

Insects

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Rhynchophorus ferrugineus, commonly known as red palm weevil (RPW), is a high-risk insect pest that has become a threat to many important palm species. There are several dominant factors that lead to the successful infestation of RPW, including its stealthy lifestyle, highly chitinized mouthpart, and high fecundity rate. Due to that, millions of dollars of losses have been suffered by many countries invaded by RPW. Several methods have been designed to control its invasion, including the usage of insecticides, but many cause resistance and environmental pollution. Therefore, an environmentally friendly insecticide that targets specific systems or pathways in RPW is urgently needed. One of the potential targets is the digestive system of RPW, as it is the major interface between the insect and its plant host. The related knowledge of RPW’s digestive system, such as the anatomy, microflora, transcriptomic analysis, and proteomic analysis, is important to understand its effects on RPW’s survival. Several data from different omics regarding the digestive systems of RPW have been published in separate reports. Some of the potential targets have been reported to be inhibited by certain potential insecticides, while other targets have not yet been tested with any inhibitors. Hence, this review may lead to a better understanding on managing infestations of RPW using the system biology approach for its digestive system.

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Biochemical and toxicological characteristics of polyphenol oxidase from red palm weevil Rhynchophorus ferrugineus (Olivier) (Coleoptera: Curculionidae)

Ghanem,

Abd-Elaziz,

Mohamed

2025

Comparative Biochemistry and Physiology Part C: Toxicology &

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Defense status in larval stage of red palm weevil Rhynchophorus ferrugineus (Olivier) (Coleoptera: Curculionidae)

Cited by 4 publications

References 67 publications

Rhynchophorus ferrugineus larvae: A novel source for combating broad-spectrum bacterial and fungal infections

Rhynchophorus ferrugineus larvae: A novel source for combating broad-spectrum bacterial and fungal infections

A Review on Digestive System of Rhynchophorus ferrugineus as Potential Target to Develop Control Strategies

Biochemical and toxicological characteristics of polyphenol oxidase from red palm weevil Rhynchophorus ferrugineus (Olivier) (Coleoptera: Curculionidae)

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