Degradable, antibacterial silver exchanged mesoporous silica spheres for hemorrhage control

Toward bioactive yet antibacterial surfaces

“…Although it is generally considered that a safe Ag concentration ranges between 0.1 ppb (minimal value at which the bactericidal effect is possible) and 10 ppm (appearance of toxic effect) [5], the available data are rather contradictive. For instance, toxic effect was reported for films that demonstrated both low and high Ag + ion release, for instance 1-2 ppb [6,7], 80 ppb [5], 0.1-0.2 ppm [8,9], 1 ppm [10]. Note that different Ag species are http://dx.doi.org/10.1016/j.colsurfb.2015.06.059 0927-7765/© 2015 Elsevier B.V. All rights reserved.…”

Degradation and hemostatic properties of polyphosphate coacervates

“…This platelet adhesion test was adapted from Ong et al [22] and Dai et al [23], with platelet separation from the blood achieved using a protocol developed by Cazenave et al [24]. Rat blood was collected by a certified veterinarian according to the university's animal ethics regulations.…”

Nanoporosity improved water absorption, in vitro degradability, mineralization, osteoblast responses and drug release of poly(butylene succinate)-based composite scaffolds containing nanoporous magnesium silicate compared with magnesium silicate

“…20 Briefly, NMS was synthesized by a modified template-induced and self-assembling method using cetyl trimethyl ammonium bromide (CTAB) as a structure-directing agent, magnesium nitrate hexahydrate as a magnesium source and tetraethyl orthosilicate as a silica source. The samples were successively centrifuged, dried and calcinated to obtain the final white powder.…”