Delayed anaphylactoid reaction in a worker exposed to chromium

Dr, Moller; Sm, Brooks; Di, Bernstein; Cassedy, K; Enrione, M; Il, Bernstein

doi:10.1016/0091-6749(86)90179-x

Cited by 51 publications

(24 citation statements)

References 21 publications

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“…This study shows a relation between exposure to welding fumes and asthma, but we cannot pinpoint the causative exposure. Asthma has been described after welding on stainless steel (20)(21)(22)(23), and a slightly increased risk for asthma has been seen in 2 epidemiologic studies (24)(25). However, in a review in 1991 the evidence was not regarded as strong enough to support a causal relation between plain steel welding and asthma-onset (26).…”

Section: Discussionmentioning

confidence: 99%

Adult-onset asthma and occupational exposures

Järvholm¹,

Brisman²,

Hagberg³

et al. 1999

Scand J Work Environ Health

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Section: Discussionmentioning

confidence: 99%

Adult-onset asthma and occupational exposures

Järvholm¹,

Brisman²,

Hagberg³

et al. 1999

Scand J Work Environ Health

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“…Cutaneous and anaphylactic reactions have occasionally been reported during SICs [136][137][138][139][140]. Skin contact with occupational agents should be reduced as much as possible during SIC by using protective clothes or closed-circuit delivery systems.…”

Section: Cutaneous and Anaphylactic Reactionsmentioning

confidence: 99%

Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement

et al. 2014

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This consensus statement provides practical recommendations for specific inhalation challenge (SIC) in the diagnosis of occupational asthma. They are derived from a systematic literature search, a census of active European centres, a Delphi conference and expert consensus. This article details each step of a SIC, including safety requirements, techniques for delivering agents, and methods for assessing and interpreting bronchial responses. The limitations of the procedure are also discussed.Testing should only be carried out in hospitals where physicians and healthcare professionals have appropriate expertise. Tests should always include a control challenge, a gradual increase of exposure to the suspected agent, and close monitoring of the patient during the challenge and for at least 6 h afterwards. In expert centres, excessive reactions provoked by SIC are rare.A positive response is defined by a fall in forced expiratory volume in 1 s o15% from baseline. Equivocal reactions can sometimes be clarified by finding changes in nonspecific bronchial responsiveness, sputum eosinophils or exhaled nitric oxide. The sensitivity and specificity of SIC are high but not easily quantified, as the method is usually used as the reference standard for the diagnosis of occupational asthma. @ERSpublications ERS Task Force: a statement on specific inhalation challenges in the diagnosis of occupational asthma

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“…For those subjects who demonstrate LAR or DAR, initiating or increasing inhaled steroids for a few days is indicated. Cutaneous and anaphylactoid reactions have occasionally been described [65,66].…”

Section: Pitfallsmentioning

confidence: 99%

Inhalation challenges with agents causing occupational asthma

Vandenplas¹,

Jl²

1997

Eur Respir J

124

103

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Occupational asthma (OA) is steadily emerging as the principal cause of respiratory disease due to the workplace environment. One of the key means to ascertain diagnosis of OA is specific inhalation challenge (SIC) with occupational agents. This review: 1) describes the methodology of SIC, with a special emphasis on procedures aimed at increasing the safety and validity of these tests; and 2) outlines the roles of SIC in the diagnosis of OA in clinical and medicolegal assessment, epidemiological studies, surveillance programmes and the investigation of the pathophysiological mechanisms of asthma and OA. We discuss areas of future development, including the development of apparatus which allows exposure of subjects to low and stable concentrations of the occupational agent and the assessment of preventive procedures.

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Delayed anaphylactoid reaction in a worker exposed to chromium

Cited by 51 publications

References 21 publications

Adult-onset asthma and occupational exposures

Adult-onset asthma and occupational exposures

Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement

Inhalation challenges with agents causing occupational asthma

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