Delayed electrocardiographic changes after percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy

Guo, Hangyuan; Wang, Ping; Xing, Yangbo; Peng, Fang; Jiang, Jun; Bian, Yang; You, Binquan; Qiu, Yufang; Lee, Jong–Dae

doi:10.1016/j.jelectrocard.2006.12.003

Cited by 6 publications

(4 citation statements)

References 17 publications

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“…AF contributes to the exacerbation of symptoms and the development of heart failure in patients with HCM . It has been shown that increased LA afterload in HCM corresponds well with LV diastolic dysfunction and that septal reduction therapy improves the severity of mitral regurgitation . While septal reduction therapy including ASA is not primarily performed to reduce subsequent AF burden in HCM, the favorable anatomic correction leading to reduced mitral regurgitation and decreased LA afterload—as demonstrated in our study—might reasonably be expected to lead to a corresponding decrease in the AF.…”

Section: Discussionsupporting

confidence: 50%

“…AF confers increased risk of all‐cause mortality, including that due to heart failure and thromboembolic events and is associated with worsened exercise capacity and symptoms impacting quality of life . Despite multiple cohort studies of patients undergoing ASA for symptomatic HCM, , none has reported on the incidence of AF. We evaluated the incidence of AF following ASA for symptomatic HCM.…”

mentioning

confidence: 99%

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Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

Moss

Zipse

Krantz

et al. 2016

Noninvasive Electrocardiol

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Section: Discussionsupporting

confidence: 50%

mentioning

confidence: 99%

Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

Moss

Zipse

Krantz

et al. 2016

Noninvasive Electrocardiol

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“…A total of 40 studies including 22 ASA studies 4,12-32 and 23 SM cohorts 10,11,18,25,30,[32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49] S1.…”

Section: Resultsmentioning

confidence: 99%

Alcohol septal ablation vs myectomy for symptomatic hypertrophic obstructive cardiomyopathy: Systematic review and meta‐analysis

Kheiri

Osman

Barbarawi

et al. 2018

Clinical Cardiology

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Background: Surgical myectomy (SM) and Alcohol septal ablation (ASA) are effective therapies for patients with hypertrophic cardiomyopathy who remain symptomatic despite medical therapy. A plethora of data has recently emerged on the long-term outcomes of these procedures.We hence sought to perform an updated meta-analysis comparing both procedures.Methods: Studies reporting long-term (>3-years) outcomes of SM and/or ASA were included.The primary endpoint was all-cause mortality. Secondary endpoints included cardiovascular mortality, sudden cardiac death (SCD), reintervention, and complications including death, pacemaker implantation, and stroke.Results: Twenty-two ASA cohorts (n = 4213; follow-up = 6.6-years) and 23 SM cohorts (n = 4240; follow-up = 6.8-years) were included. Septal myectomy was associated with higher periprocedural mortality and stroke (2% vs 1.2%, P = 0.009 and 1.5% vs 0.8% P = 0.013, respectively), but ASA was associated with more need of pacemaker (10% vs 5%, P < 0.001). During long-term follow-up, all-cause mortality, cardiovascular mortality, and sudden cardiac death rates were 1.5%, 0.4%, and 0.3% per person-year in the ASA group and 1.1%, 0.5%, and 0.3% per person-year in the SM group (P = 0.21, P = 0.53, P = 0.43), respectively. Repeat septal reduction intervention(s) were more common after ASA (11% vs 1.5%, P < 0.001). Conclusion:Compared with SM, ASA is associated with lower periprocedural mortality and stroke but higher rates of pacemaker implantations and reintervention. However, there was no difference between ASA and SM with regards to long-term all-cause mortality, cardiovascular mortality, or SCD.

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“…Several studies have reported high functional and hemodynamic success of ASA in symptomatic patients with HOCM [2][3][4] . Acute electro cardiographic changes seen in previous studies after ASA are right bundle branch block, STsegment deviation, and Q wave formation [5,6] . We present a case of left septal fascicular block (LSFB) which appeared secondary to ASA for HOCM.…”

Section: Introductionmentioning

confidence: 88%

Left Septal Fascicular Block Following Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy

Gül

Pérez‐Riera

Haseeb

et al. 2019

Journal of Atrial Fibrillation

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Left septal fascicular block, or blockage of the middle fibers of the left bundle branch, is known to be suggestive of a critical proximal obstruction of the left anterior descending coronary artery before its first septal perforator branch. We describe the case of a 68-year-old male who exhibited this transient intraventricular dromotropic disturbance following alcohol septal ablation for hypertrophic obstructive cardiomyopathy.

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Delayed electrocardiographic changes after percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy

Cited by 6 publications

References 17 publications

Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

Alcohol septal ablation vs myectomy for symptomatic hypertrophic obstructive cardiomyopathy: Systematic review and meta‐analysis

Left Septal Fascicular Block Following Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy

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