2012
DOI: 10.1097/ccm.0b013e31822d71a6
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Delayed enteral feeding impairs intestinal carbohydrate absorption in critically ill patients*

Abstract: In critical illness, delaying enteral feeding is associated with a reduction in small intestinal glucose absorption, consistent with the reduction in mucosal integrity after nutrient deprivation evident in animal models. The duration of both mechanical ventilation and length of stay in the intensive care unit are prolonged. These observations support recommendations for "early" enteral nutrition in critically ill patients.

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Cited by 62 publications
(36 citation statements)
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“…Nine RCTs were extracted based on the systematic review conducted for this CQ 308, 309, 310, 311, 312, 313, 314, 315, 316. Mortality rate was assessed by eight RCTs; infection frequency, the length of ICU stay, and duration of ventilation were assessed by seven RCTs, and length of hospital stay was assessed by four RCTs.…”
Section: Cq13: Nutritionmentioning
confidence: 99%
“…Nine RCTs were extracted based on the systematic review conducted for this CQ 308, 309, 310, 311, 312, 313, 314, 315, 316. Mortality rate was assessed by eight RCTs; infection frequency, the length of ICU stay, and duration of ventilation were assessed by seven RCTs, and length of hospital stay was assessed by four RCTs.…”
Section: Cq13: Nutritionmentioning
confidence: 99%
“…Group 2 and 3 patients with possible LRTI had significantly more supplemental oxygen-free days than patients with probable/proven LRTI (29 days [IQR, 28-29 days] vs 17 days [IQR, 0-29 days]; P < .0001). Of the 9 subjects who died by day 28, only Death by day 28 4 (2) 6 (11) 0 (0) 6 (22) 5 (15) 0 (0) 5 (33) 0 (0) 11 (26) 3 had any supplemental oxygen-free days in that period. Thus, calculation of supplemental oxygen-free days per definition 2 did not change medians for any groups ( Supplementary Table 4).…”
Section: Supplemental Oxygen-free Days Following Rsv Infection Diagnosismentioning
confidence: 99%
“…A demora de três dias em iniciar a NE, a doença crítica e o estresse oxidativo, conduzem a uma redução no tamanho da vilosidade e na profundidade da cripta, assim como no aumento na permeabilidade intestinal (o que permite o escape de bactérias Gram negativas), ulceração e atrofia da mucosa (Chan, 2009). A presença de nutrientes no lúmen intestinal pode prevenir estes efeitos deletérios (Nguyen et al, 2012) …”
Section: Alterações Metabólicas No Animal Enfermounclassified
“…A infusão de aminoácidos deve ser diminuída em pacientes com alterações renais ou encefalopatia hepática e aumentada em enfermidades que provoquem perdas profundas e contínuas de proteína como, por exemplo, enteropatias ou peritonite (Lehninger, 2006, Liu et al, 2012, Nguyen et al, 2012. Dois aminoácidos que merecem destaque em nutrição clínica de cães são a arginina e a glutamina.…”
Section: Aminoácidosunclassified