Delayed gastric emptying in dyspeptic chronic hemodialysis patients

Vlem, Bruno Van; Schoonjans, Renaat; Vanholder, Raymond; Vos, Martine De; Vandamme, Wouter; Laecke, Steven Van; Lameire, Norbert

doi:10.1053/ajkd.2000.19094

Cited by 84 publications

(81 citation statements)

References 25 publications

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“…This finding is similar to the results published in critically ill adult patients with acute renal failure (Fiaccadori et al, 2004). The higher incidence of complications in patients with acute renal failure could be due the gastrointestinal motility disorders associated with the uremia (Van Vlem et al, 2000) and/or the greater clinical severity of patients with acute renal failure indicated by the higher incidence of shock, the need for high drugs of vasoactive doses and multiorgan failure (Fernández et al, 2005).…”

Section: Discussionsupporting

confidence: 88%

Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition

et al. 2007

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Objective: To study the risk factors for gastrointestinal complications related to enteral nutrition in critically ill children. Design: A prospective, observational study. Setting: Pediatric intensive care unit Subjects: Five hundred and twenty-six critically ill children who received transpyloric enteral nutrition(TEN). Methods: Univariate and multivariate logistic regression analysis were used to identify risk factors for gastrointestinal complications Results: Sixty six patients (11.5%) presented gastrointestinal complications, 33 (6.2%) abdominal distension and/or excessive gastric residue, 34 (6.4%) diarrhea, one gastrointestinal bleeding, three necrotizing enterocolitis and one duodenal perforation. Enteral nutrition was definitively suspended because of gastrointestinal complications in 11 (2.1%) patients. Fifty patients (9.5%) died. Gastrointestinal complications were more frequent in the patients who died. Death was related to complications of the nutrition in only one patient. The frequency of gastrointestinal complications was significantly higher in children with shock, acute renal failure, hypokalemia, hypophosphatemia and in those receiving dopamine, epinephrine and vecuronium. The stepwise multivariate logistic regression analysis showed that the most important factors associated with gastrointestinal complications were shock, epinephrine at a rate higher than 0.3 mg/kg/min and hypophosphatemia. Conclusions: The tolerance of TEN in critically ill children is good, although the incidence of gastrointestinal complications is higher in patients with shock, acute renal failure, hypokalemia, hypophosphatemia, and those receiving epinephrine, dopamine, and vecuronium.

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Section: Discussionsupporting

confidence: 88%

Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition

et al. 2007

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“…16 However, there have been only few studies on the differences in the prevalence of GERD between patients undergoing peritoneal dialysis and those undergoing hemodialysis.…”

Section: Discussionmentioning

confidence: 99%

Is There a Difference in the Prevalence of Gastroesophageal Reflux Disease between Peritoneal Dialysis and Hemodialysis Patients?

Song

Kim

Lee

et al. 2013

Korean J Gastroenterol

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“…Only a few studies (Lin et al, 1997;Ko et al, 1998;Lee et al, 2000) have investigated gastric myoelectrical activity in patients with CRF. On the other hand, several studies evaluating gastric emptying in patients with CRF have yielded conflicting results; in some of these (Brown-cartwright et al, 1988;Dumitrascu et al, 1995;Kao et al, 1996;Van Vlem et al, 2001;Hubalewska et al, 2004) gastric emptying was found to be delayed, while in others (Wright et al, 1984;McNamee et al, 1985;Soffer et al, 1987) it remained unchanged. In most of these studies, it is not clear whether the patients were receiving dialysis.…”

Section: Discussionmentioning

confidence: 99%

“…Two large studies (Perri et al, 1998;Sarnelli et al, 2003) demonstrated that patients with delayed gastric emptying for solids are more likely to report postprandial bloating, nausea and epigastric pain. One report (Van Vlem et al, 2000) showing that there was a significant difference in gastric emptying between dyspeptic and nondyspeptic hemodialysis patients has been published. These data support our results.…”

Section: Discussionmentioning

confidence: 99%

“…Several reports (Brown-cartwright et al, 1988;Dumitrascu et al, 1995;Kao et al, 1996;Van Vlem et al, 2001;Hubalewska et al, 2004;Wright et al, 1984;McNamee et al, 1985;Soffer et al, 1987) evaluating gastric emptying in patients with CRF have yielded conflicting results. The discrepancies among these findings may be attributed to the methods used to measure gastric emptying or differences in the patients' conditions (i.e., on hemodialysis, on continuous ambulatory peritoneal dialysis, or at the predialysis stage).…”

Section: Introductionmentioning

confidence: 99%

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Improvement of gastric motility by hemodialysis in patients with chronic renal failure

Adachi

Kamiya

Hirako

et al. 2007

J. Smooth Muscle Res.

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Background: Gastrointestinal (GI) symptoms are common in patients with chronic renal failure (CRF). We have previously demonstrated that patients with predialysis endstage renal disease showed a high prevalence of GI symptoms and gastric hypomotility, and that gastric hypomotility appears to be an important factor in generating GI symptoms. However, it is not clear whether impaired gastric motor function would improve after hemodialytic treatment. Aims: To examine the relationship between gastric motor function and GI symptoms in CRF patients on hemodialysis. Methods: The study was performed in 19 patients with CRF treated with hemodialysis for more than six months and in 12 matched healthy controls. GI symptom severity was quantified in all patients. Gastric motility was evaluated with cutaneously recorded electrogastrography (EGG) and gastric emptying of semi-solid meals using the 13 C-acetic acid breath test. Results: Six patients had no symptoms, and 11 had slight GI symptoms with a total symptom score of less than 5. Compared with controls, CRF patients revealed no differences in gastric motility parameters, with the exception of a lower percentage of normogastria in EGG at fasting state. Eleven patients had normal gastric motor function (Group A), and eight showed abnormalities of either gastric myoelectrical activity or gastric emptying (Group B). There was no difference in symptom score between Group A and Group B. Conclusions: More than half of the patients with CRF on hemodialysis demonstrated normal gastric motility, and no or slight GI symptoms. Hemodialytic treatment may improve impaired gastric motility and reduce GI symptoms in patients with CRF.

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Delayed gastric emptying in dyspeptic chronic hemodialysis patients

Cited by 84 publications

References 25 publications

Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition

Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition

Is There a Difference in the Prevalence of Gastroesophageal Reflux Disease between Peritoneal Dialysis and Hemodialysis Patients?

Improvement of gastric motility by hemodialysis in patients with chronic renal failure

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