Delayed healing in full-thickness wounds treated with aluminum chloride solution

Sawchuk, William S.; Friedman, Kenneth J.; Manning, Thomas O.; Pinnell, Sheldon R.

doi:10.1016/s0190-9622(86)70261-2

Cited by 30 publications

(27 citation statements)

References 9 publications

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“…We used 20% aluminum chloride for hemostasis. Monsel's solution and 30% aluminum chloride have both been shown to delay wound healing 30 and to contribute to tissue necrosis, perhaps increasing wound depth and enhancing the cure rate. Using only pressure for hemostasis with curettage alone, Reymann 11 had a somewhat higher recurrence rate than what we report.…”

Section: Discussionmentioning

confidence: 99%

Treatment of basal cell carcinoma with curettage alone

Barlow

Zalla

Kyle

et al. 2006

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

Treatment of basal cell carcinoma with curettage alone

Barlow

Zalla

Kyle

et al. 2006

Journal of the American Academy of Dermatology

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“…Painful paresthesias or tissue irritation that can delay wound healing (Larson, 1988;Sawchuk, Friedman, Manning, & Pinnell, 1986) Ferrous subsulfate solution (Monsel's solution)…”

Section: Aluminum Chloride (Drysol)mentioning

confidence: 99%

“…Risk of tattooing of skin; increased erythema, dermal fibrosis (Armstrong, Nichols, & Pachance, 1986), dyspigmentation, delays in reepithelialization, and increased incidence of wound infection (Sawchuk et al, 1986) Silver nitrate Rare risk of tattoo with deposition of silver particles; burning sensation upon application (Palm & Altman, 2008) Zinc paste (''Moh's paste'')…”

Section: Aluminum Chloride (Drysol)mentioning

confidence: 99%

Aluminum Chloride

Totri

Jacob

2015

Journal of the Dermatology Nurses' Association

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By definition, a drug is a medicine or substance that exerts a physiologic affect on an organism. In dermatology, medications and substances are utilized on a daily basis from topical treatments to anesthetics in micrographic surgery. The purpose of this column is to focus on some of the more common drugs used in dermatology, specifically their mechanism of action and routine alternatives (if available). This brief focuses on the utilization of aluminum chloride in dermatologic hemostasis and provides a table of alternative caustic agents used for hemostasis.

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“…However literatures from dermatologic surgery could be helpful because Monsel's solution (20% ferric subsulfate) has been popularly used and investigated in the dermatologic field 69,70. Although being an effective local hemostatic measure, Monsel's solution resulted in several post-operative complications such as delayed re-epithelization and dyspigmentation on soft tissue 59,60,61,62,63. Armstrong et al compared the effect of collagen matrix and Monsel's solution on punch biopsy wounds, and observed more inflammation, higher incidence of wound infection, and slower re-epithelialization rate on the group treated by Monsel's solution at 4 weeks 61…”

Section: Reviewmentioning

confidence: 99%

Biologic response of local hemostatic agents used in endodontic microsurgery

et al. 2014

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Appropriate use of local hemostatic agent is one of the important factors on the prognosis of endodontic microsurgery. However, most investigations to date focus on the hemostatic efficacy of the agents, whereas their biologic characteristics have not received enough attention. The purpose of this paper was to review the biologic response of local hemostatic agents, and to provide clinical guidelines on their use during endodontic microsurgery. Electronic database (PUBMED) was screened to search related studies from 1980 to 2013, and 8 clinical studies and 18 animal studies were identified. Among the materials used in these studies, most widely-investigated and used materials, epinephrine, ferric sulfate (FS) and calcium sulfate (CS), were thoroughly discussed. Influence of these materials on local tissue and systemic condition, such as inflammatory and foreign body reaction, local ischemia, dyspigmentation, delayed or enhanced bone and soft tissue healing, and potential cardiovascular complications were assessed. Additionally, biological property of their carrier materials, cotton pellet and absorbable collagen, were also discussed. Clinicians should be aware of the biologic properties of local hemostatic agents and their carrier materials, and should pay attention to the potential complications when using them in endodontic microsurgery.

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Delayed healing in full-thickness wounds treated with aluminum chloride solution

Cited by 30 publications

References 9 publications

Treatment of basal cell carcinoma with curettage alone

Treatment of basal cell carcinoma with curettage alone

Aluminum Chloride

Biologic response of local hemostatic agents used in endodontic microsurgery

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