2021
DOI: 10.3389/fsurg.2021.732603
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Delayed Leukoencephalopathy and Foreign Body Reaction After Endovascular Treatment in Patients With Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage—A Systematic Review of the Literature

Abstract: Background: Delayed leukoencephalopathy and foreign body reaction are rare complications after endovascular treatment of intracranial aneurysms. However, cases are increasingly being described, given the rising case numbers and complexity.Methods: Clinical presentation, differentials, diagnostics, treatment, and formerly published data were reviewed in light of available cases. A systematic search of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyse… Show more

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Cited by 3 publications
(5 citation statements)
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“…Gadolinium enhancement is either solid or rim-shaped. Partially, low signals in SWI in the fluid-attenuated inversion recovery (FLAIR) hyperintensities are reported, probably due to deposition of microembolic paramagnetic coil-related materials [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Gadolinium enhancement is either solid or rim-shaped. Partially, low signals in SWI in the fluid-attenuated inversion recovery (FLAIR) hyperintensities are reported, probably due to deposition of microembolic paramagnetic coil-related materials [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ].…”
Section: Discussionmentioning
confidence: 99%
“…Eventually, in such cases, prolonged immunosuppressive therapy may be considered [ 7 ]. Apart from clinical examination and evaluation of new neurological symptoms, clinicians should monitor closely for post EVT radiologic parenchymal edematous changes in follow-up brain MRIs, suggesting immune-mediated leukoencephalopathy in order to initiate immunological treatment swiftly and effectively [ 17 ].…”
Section: Discussionmentioning
confidence: 99%
“…Many symptomatic patients received a corticosteroid regimen and recovered almost fully after treatment. [ 10 ] Early high dose followed by low dose ongoing corticosteroid treatment was recommended for timely remission. [ 10 ] However, a few mildly symptomatic patients were observed without any specific treatment like our patient and recovered well.…”
Section: Discussionmentioning
confidence: 99%
“…[ 10 ] Early high dose followed by low dose ongoing corticosteroid treatment was recommended for timely remission. [ 10 ] However, a few mildly symptomatic patients were observed without any specific treatment like our patient and recovered well. [ 10 ] Therefore, we believe that a steroid regimen is not always needed, especially for asymptomatic DLE patients.…”
Section: Discussionmentioning
confidence: 99%
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