Delivery modulation in silica mesoporous supports via functionalization in the pore outlets with a Zn(II)–bis(2-pyridylmethyl)amine complex

Abstract

ElsevierBartovsky ., P.; Ribes, À.; Agostini, A.; Benito Beorlegui, Á.; Martínez-Máñez, R. (2014). Delivery modulation in silica mesoporous supports via functionalization in the pore outlets with a Zn(II) bis(2-pyridylmethyl)amine complex. release. The delivery observed was clearly related with the ability of the anion to form complexes with the Zn(II)-dipicolylamine groups and with the size and charge of the anion.

Molecular and supramolecular switches on mesoporous silica nanoparticles

“…Switches responsive to anions have been exploited remarkably to fabricate gate-like ensembles combined with MSNs due to their coordinating properties with various metal ions or polyamines. 136 A supramolecular switch triggered by anions was also reported by Martı ´nez-Ma ´n ˜ez et al 137 MSNs were immobilized with Zn(II)-bis(2-pyridylmethyl)amine complexes on the surfaces. The loaded dyes were released by the addition of selected anions, such as F À , Cl À , Br À , I À , AcO À , BzO À , SO 4 2À , NO 3 À , PO 4 3À , P 2 O 7 2À , ATP, ADP and AMP, which formed complexes with Zn(II)-dipicolylamine groups.…”

Anions as Triggers in Controlled Release Protocols from Mesoporous Silica Nanoparticles Functionalized with Macrocyclic Copper(II) Complexes

“…Someo fus have prepared silica mesoporous nanoparticles loaded with Ru(bipy) 3 2 + (bipy = bipyridine) dye and functionalized on the externals urface with Zn 2 + -2,2'-dipicolylamine complexes.T he releaseo ft he entrapped dye was finely tuned upon the addition of selected anions. [18] Other transition-metal complexes have also been used as caps to develop pH-triggered hybrid materials. Along these lines, Jung and co-workers prepared hollow silica mesoporous nanoparticles loaded with curcumin and capped by Cu 2 + -phenanthroline complexes.…”

“…[24] Yet, as far as we know,s tudies on the interactions of metal complexes with anionsi nr elation to the modulation of mass transport in gated materials are rare. [18] Nevertheless, these studies may be importantt o gain ab etter understanding of the role played by anionsi n gated ensembles and the interactions that negatively charged speciesand complexes display on functionalizeds urfaces.…”

“…Some of us have prepared silica mesoporous nanoparticles loaded with Ru(bipy) 3 2+ (bipy=bipyridine) dye and functionalized on the external surface with Zn 2+ –2,2′‐dipicolylamine complexes. The release of the entrapped dye was finely tuned upon the addition of selected anions …”

“…In fact, many studies have been conducted in solution and have demonstrated that metal complexes are able to form complexes with a large number of anions by either hydrogen‐bonding interactions, coordination to the metal center, or electrostatic attractive forces . Yet, as far as we know, studies on the interactions of metal complexes with anions in relation to the modulation of mass transport in gated materials are rare . Nevertheless, these studies may be important to gain a better understanding of the role played by anions in gated ensembles and the interactions that negatively charged species and complexes display on functionalized surfaces.…”