Demographic Profile, Clinical Presentation & Angiographic Findings in 637 Patients with Coronary Heart Disease

Abstract

Cardiovascular diseases are the commonest cause of death globally and are the major contributor to the burden of premature mortality and morbidity. This study analyses various clinical presentations, conventional risk factors, pattern and severity of coronary heart disease on angiography among 637 patients with coronary heart disease and adult congenital heart disease who underwent cardiac evaluation at National Institute of Cardiovascular Disease (NICVD), Dhaka between January 2007 to December 2008. Among them 547 (85.9%) were male and 90 (14.1%) were female. All of them were between 22 to 76 years of age with mean age 50.15±8.8. One hundred sixty nine (25.9%) patients had chronic stable angina & 398 (62.48%) patients subjected for coronary angiography for acute coronary syndrome and or old myocardial infarction and 74 (11.62%) patients with vascular and adult congenital heart disease prior to surgical treatment. Most prevalent risk factors were smoking (60%) and dyslipidaemia (60%). Thirty five percent patients were hypertensive and 10% patient had diabetes. Normal epicardial coronaries were documented in 25.59% patients which includes the patients who underwent coronary angiography prior to surgical treatment. Ninety three (14.6%) had single vessel disease, 119 (18.68%) had double vessel disease, 259 (40.66%) had triple vessel disease and 3 (0.47%) had isolated left main disease. Key words: Coronary angiogram; Coronary artery disease. DOI: http://dx.doi.org/10.3329/fmcj.v6i2.9206 FMCJ 2011; 6(2): 82-85

Association of Left Coronary Dominance with In- Hospital Adverse Outcomes after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome

“…In another study in Bangladesh male female ratio was 7.01:1. 8 Female are less prone to developed IHD in premenopausal age due to protective role of estrogen, moreover smoking as a risk factor of IHD is less common in our country among female, which may explain male predominance of IHD.…”

Atherosclerosis Is Associated with Neutrophil Lymphocyte Ratio As An Inflammatory Marker in Type 2 Diabetes Mellitus Patients with Coronary Artery Disease

“…21 The incidence is much greater in developing countries. 22 CAD occurs at any adult age, but it is the disease of middle and old age. In our study, the mean age of the patients in Group I (DM with CAD) was 54.73 (±8.94) years as compared to 56.59±13.63 years and 58.01±12.9 years, studies done by Assiri et al (2012) and Al-Saif et al (2011).…”

Occurrence of coronary artery disease in patients with type 2 diabetes mellitus can be predicted by neutrophil lymphocyte ratio

“…18 e incidence is much greater in developing countries. 5 CAD occurs at any adult age, but it is the disease of middle and old age. In our study, the mean age of the patients in Group A (DM with CAD) was 54.73 (±8.94) years as compared to 56.59±13.63 years and 58.01±12.9 years, studies done by Assiri A S et al and Al-Saif SM et al 18,19 It was 52.0±8.6 years in a study reported by Siddique MA et al and 56.6 years by Ullah M et al in Bangladesh.…”

“…Several mechanisms are likely to contribute to the accelerated atherosclerosis and increased chronic heart disease (CHD) risk in patients with type 2 diabetes mellitus. 4,5 Multiple hypothesis exist to explain the occurrence of premature coronary atherosclerosis in diabetes but the consensus is that it is multifactorial. Important factors include dyslipidemia, hypertension, hypercoagulability, poor glycemic control, smoking, obesity and lack of physical activity.…”

“…3,4 Coronary artery disease (CAD) is the most common cause of myocardial infarction. 5 Coronary artery disease progresses before the rst onset of symptoms. So, most individual with CAD show no evidence of disease for prolong period.…”