Demonstration of in-vivo Multi-Probe Tracker Based on a Si/CdTe Semiconductor Compton Camera

Abstract

By using a prototype Compton camera consisting of silicon (Si) and cadmium telluride (CdTe) semiconductor detectors, originally developed for the ASTRO-H satellite mission, an experiment involving imaging multiple radiopharmaceuticals injected into a living mouse was conducted to study its feasibility for medical imaging. The accumulation of both iodinated methylnorcholestenol and Sr into the mouse's organs was simultaneously imaged by the prototype. This result implies that the Compton camera is expected to become a multi-probe tracker available in nuclear medicine and small animal imaging.Index Terms-Astrophysics, nuclear medicine, Si/CdTe semiconductor compton camera, small animal imaging.

Design and performance of Soft Gamma-ray Detector onboard the Hitomi (ASTRO-H) satellite

“…Taking advantage of 15 years of development, [11][12][13]31,[36][37][38][39][40][41][42] the SGD Compton camera is optimized to detect gamma rays up to 600 keV. A Compton camera consists of a stack of 32 layers of 0.6-mm-thick Si pixel sensors 43 followed by 8 layers of 0.75-mm-thick CdTe pixel sensors, 44,45 surrounded by 2 layers of 0.75-mm-thick CdTe pixel sensors on the four sides as shown in Fig.…”

Three-dimensional and Multienergy Gamma-ray Simultaneous Imaging by Using a Si/CdTe Compton Camera

“…The efficiency of the camera is 0.23 Hz/MBq at 10 cm (356 keV). The detailed configuration of this Si/CdTe Compton camera was described by Takeda et al (12).…”

Visualization of radioactive substances with a Si/CdTe Compton Camera

“…The resolution of catering angle (Angular Resolution Measure or ARM) was 3.5 degree (FWHM) and 2.5 degree (FWHM) at 356 keY and 511 keY, respectively. The performance and the responses of the camera has been studied quite intensively and reported in other literatures [16], [17], [18], [19].…”