Densitometric Quantification and Optimization of Polyphenols in Phyllanthus maderaspatensis by HPTLC

Thymoquinone-rich black cumin oil attenuates ibotenic acid-induced excitotoxicity through glutamate receptors in Wistar rats

“…The oil fraction of black cumin, comprising both the essential and fixed oils, has been identified as its primary bioactive component ( Mazaheri et al, 2019 ). While linoleic acid forms the major part of the fixed oil, thymoquinone (TQ) was identified as the most abundant molecule in the essential oil fraction ( Gawron et al, 2021 ).Various studies have demonstrated the beneficial effects of natural compounds ( Thajudeen et al, 2022 , Rajasree et al, 2022 , Ilyas et al, 2022 ). Several studies have linked the pharmacological effects of black cumin oil (antimicrobial, anti-inflammatory, antihypertensive, anti-obese, hypoglycemic, hypolipidemic, hepatoprotective, and neuroprotective) to its TQ content Kooti et al, 2016 , Mukhtar et al, 2019 ).…”