Dental Status and Periodontal Health of Patients with Phenylketonuria in Latvia

Abola, Iveta; Emulina, Darta Elizabete; Skadiņš, Ingus; Brinkmane, Anda; Gailīte, Linda; Kreile, Madara

doi:10.15644/asc56/2/2

Cited by 6 publications

(8 citation statements)

References 28 publications

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“…However, there are various studies that show that patients with PKU have more oral complications than normal ones. For example, Ābola et al 17 reported that the dental status and periodontal health of PKU patients were found to be significantly inferior compared to healthy controls associated with the regular consumption of PKU formula and the difficulties which mentally and/or physically disabled PKU patients experience with their oral hygiene. But there is a big difference with our study, we have performed a study on children with ages around 4 years while the median age of people in Ābola et al 17 study was 22 years.…”

Section: Discussionmentioning

confidence: 99%

“…For example, Ābola et al 17 reported that the dental status and periodontal health of PKU patients were found to be significantly inferior compared to healthy controls associated with the regular consumption of PKU formula and the difficulties which mentally and/or physically disabled PKU patients experience with their oral hygiene. But there is a big difference with our study, we have performed a study on children with ages around 4 years while the median age of people in Ābola et al 17 study was 22 years. On the other hand, Ballikaya et al 7 reported that 67% of PKU patients have dental caries, but they also mentioned that of the patients, 85.3% did not brush their teeth regularly and 90.4% had never visited a dentist before, which makes the conclusion ambiguous.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Decayed, Missing due to Caries, and Filled Teeth Index in Children with Phenylketonuria in Comparison to Normal Population

Ghasemi¹,

Namvar²,

Mansori³

2023

Turkish Archives of Pediatrics

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Objective: Management of patients with phenylketonuria mainly includes limiting the content of phenylalanine in the diet. Therefore, the purpose of this study was to investigate oral problems in children with phenylketonuria compared to the healthy population as a case–control study. Materials and Methods: The subjects of the case and control groups were selected according to the inclusion criteria. First, the oral cavity and tooth were examined by a specialist dentist to indicate the decayed, missing due to caries, and filled teeth index in both groups. To investigate the level of phenylalanine and evaluate other laboratory examinations, 2 mL of blood and saliva samples was taken from the subjects. Blood and saliva phenylalanine levels were measured by high-performance liquid chromatography. Phosphorus, calcium, and pH levels were investigated through calorimetric measurement. The data were analyzed using Statistical Package for Social Sciences software. Results: There was no significant difference between the case and control groups in terms of age and sex. The average level of calcium and phosphorus in the case group was higher than in the control group. Also, the average decayed, missing due to caries, and filled teeth index in the case group was not significantly different compared to the control group. None of the above-investigated indicators had a significant relationship with each other. On the other hand, it was found that there was a positive and significant relationship between phenylalanine in blood, saliva, and pH as well as between saliva phenylalanine with decayed, missing due to caries, and filled teeth. Conclusion: The results of this study indicate a significant effect of phenylketonuria disease on calcium, phosphorus, and oral pH levels in children.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of Decayed, Missing due to Caries, and Filled Teeth Index in Children with Phenylketonuria in Comparison to Normal Population

Ghasemi¹,

Namvar²,

Mansori³

2023

Turkish Archives of Pediatrics

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“…Upon examination of the dental status and periodontal health examination of PKU patients in Latvia, a notable observation surfaced, revealing that an overwhelming majority (93%) need professional dental cleaning performed by a dental hygienist [5].…”

Section: Discussionmentioning

confidence: 99%

“…PKU patients need to be recommended to rinse their mouth with water immediately after consuming the PKU formula to counteract the acidity in their oral cavity [5]. An increased acidity in the oral cavity too often or for prolonged periods of time results in the demineralisation of tooth structures.…”

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confidence: 99%

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Survey Results of the Oral Hygiene Habits (Pre and Post Recommendations) among Phenylketonuria Patients in Latvia

Abola,

Intlere,

Brinkmane

et al. 2023

Preprint

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: Background: The aim of this study was to evaluate Phenylketonuria (PKU) patients’ oral health habits and the efficiency of tailored recommendations for PKU patients in Latvia on the correct management of oral hygiene. The-free amino acid formula can negatively impact PKU patient’s oral health as it contains a high amount of complex carbohydrates. Materials and methods: In this study with a one-month interval pre and post implementation of oral hygiene recommendations, two questionnaires regarding oral hygiene habits and knowledge were prepared and provided by trained medical personnel to be filled in for all diagnosed PKU patients in Latvia who were not lost to follow-up. Results: Based on the questionnaires among the PKU patients under 18 years of age, 27% cleaned their teeth once a day. However, 6% of patients did not engage in regular teeth brushing at all. Among PKU patients over and 18 years of age, 26% brushed their teeth only once a day. Additionally, a mere 39% of PKU patients ≥18 years of age and 17% &lt; 18 years of age incorporated flossing into their oral hygiene routine. In total, 45% of PKU patients ≥18 years of age and 44% &lt; 18 years of age visited a dentist once a year, but 40% ≥18 years of age and 39% &lt;18 years of age visited a dentist less often than once per year. After reading the recommendations, a remarkable number of PKU patients &lt; 18 years of age had improved their daily oral hygiene routine, including toothbrushing (25%) and flossing (23%). Conclusion: Given the unique dietary requirements and the implementation of these daily at-home oral health practices, motivation and regular reminders should result in better oral health of PKU patients and cooperation with clinicians.

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Evaluation of mandibular bone structure changes in phenylketonuria patients through fractal analysis and radiomorphometric indices

Duyan Yüksel,

Soydan Çabuk,

Çabuk

et al. 2024

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Dental Status and Periodontal Health of Patients with Phenylketonuria in Latvia

Cited by 6 publications

References 28 publications

Evaluation of Decayed, Missing due to Caries, and Filled Teeth Index in Children with Phenylketonuria in Comparison to Normal Population

Evaluation of Decayed, Missing due to Caries, and Filled Teeth Index in Children with Phenylketonuria in Comparison to Normal Population

Survey Results of the Oral Hygiene Habits (Pre and Post Recommendations) among Phenylketonuria Patients in Latvia

Evaluation of mandibular bone structure changes in phenylketonuria patients through fractal analysis and radiomorphometric indices

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