“…Only one case reported the use of nitrous oxide with general and local anaesthesia [96]. Some of the included clinical studies did not mention the type of anaesthetic technique used [10,14,16,17,21,35,36,39,42,44,46,49,50,51,54,55,57,59,66,68,70,74,78,79,81,82,85,89,90,93,98,102,103]. In one study the extracted tooth was re-planted after the marsupialization, however there was no enough long term follow-up [16].…”