Dentin bonding and physicochemical properties of adhesives incorporated with epigallocatechin-3-gallate

Macedo, F A A; Souza, Nayara de Oliveira; Lemos, Marcelo Victor Sidou; Paula, D M De; Santiago, Sérgio Lima; Feitosa, Victor Pinheiro

doi:10.1007/s10266-018-0367-0

Cited by 28 publications

(23 citation statements)

References 19 publications

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“…Uncured adhesive was dropped onto the molds, covered with a Mylar strip, and light cured from the top surface for 40 s: 1100 mW/cm 2 ; LED Light Curing System, (Demi Plus; Kerr Manufacturing Company, Orange, California, USA) at 2 different locations (20 s from the right; and 20 s from the left). The bottom surface was also light cured for an additional 20 s. Specimens were stored for 24 h in distilled water at 37°C prior to testing 18 .…”

Section: Methodsmentioning

confidence: 99%

“…Flexural properties were evaluated using a three-point flexural strength test performed with a universal testing machine (EMIC DL-200MF; Equipamentos e Sistemas Ltda, São José dos Pinhais, Paraná, Brazil) at a crosshead speed of 0.5 mm/min 18 . Flexural strength was determined as the load at the fracture point, and the modulus of elasticity was calculated based on recorded load deflection curves 10 .…”

Section: Methodsmentioning

confidence: 99%

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Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins

et al. 2019

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Several anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations.ObjectivesThis study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives.Material and MethodsAdhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM).ResultsNo significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups.ConclusionEGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins

et al. 2019

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“…At concentrations of 0.5% and 1% (w/v), EGCG incorporated in an adhesive resin could increase the bond strength values and the longevity of adhesive-dentin bond for 6-12 months [44,45]. In contrast to the previous investigation, the addition of 0.01 and 0.1% (w/v) of EGCG to adhesive-resin compounds did not affect the resin-dentin bond, but could reduce the solubility of the adhesive-resin in water [42].…”

Section: Dentin Modifier Dentin Pretreatment Collagen Cross-linkingmentioning

confidence: 99%

Polyphenols in Dental Applications

2020

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(1) Background: polyphenols are a broad class of molecules extracted from plants and have a large repertoire of biological activities. Biomimetic inspiration from the effects of tea or red wine on the surface of cups or glass lead to the emergence of versatile surface chemistry with polyphenols. Owing to their hydrogen bonding abilities, coordination chemistry with metallic cations and redox properties, polyphenols are able to interact, covalently or not, with a large repertoire of chemical moieties, and can hence be used to modify the surface chemistry of almost all classes of materials. (2) Methods: the use of polyphenols to modify the surface properties of dental materials, mostly enamel and dentin, to afford them with better adhesion to resins and improved biological properties, such as antimicrobial activity, started more than 20 years ago, but no general overview has been written to our knowledge. (3) Results: the present review is aimed to show that molecules from all the major classes of polyphenolics allow for low coast improvements of dental materials and engineering of dental tissues.

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“…The main polyphenol found in green tea (Camellia sinensis) and inhibitor of MMP (2 and 9) is epigallocatechin 3-gallate (EGCG). Beyond the ability to cross-link, still has an antimicrobial potential against Gram-positive and Gramnegative bacteria [33]. The application of 0.1% EGCG as a dentin pretreatment associated with an adhesive conventional 2-step design resulted in the maintenance of the bond strength after 6 months of water storage [34].…”

Section: Naturalmentioning

confidence: 99%

Dentin Biomodification Agents in Dentistry–A Critical Review

Freitas¹,

Ponte²,

Farias³

et al. 2019

ohdm

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Objective: To carry out a literature review on the dentin biomodification agents used in dental research. Methods: The PubMed database and collected literature were used as a resource for peer-reviewed articles to highlight the topics of dentin hierarchical structure, biomodification agents, and investigations of their laboratory and clinical applications. Results: Biomodification agents can be categorized as physical methods and chemical agents. Synthetic and naturally occurring chemical strategies present a distinctive mechanism of interaction with the tissue. Initially thought to be driven only by inter-or intra-molecular collagen-induced non-enzymatic collagen cross-linking, multiple interactions with other dentin components are fundamental for the long-term biomechanics and biostability of the tissue. Conclusion: Riboflavin is a physical agent that is difficult to obtain in industrial terms compared to natural extracts from plants such as proanthocyanidin that can be extracted from natural sources. Cardol and cardanol are industrial discard products and are a good choice for every day being produced on a large scale. Curcumin and chitosan have more accessibility in the extraction. Those of synthetic origin, such as glutaraldehyde have cytotoxic potential and carbodiimide has been a favorable substitute due to lower cytotoxic potential.

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Dentin bonding and physicochemical properties of adhesives incorporated with epigallocatechin-3-gallate

Cited by 28 publications

References 19 publications

Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins

Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins

Polyphenols in Dental Applications

Dentin Biomodification Agents in Dentistry–A Critical Review

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