Dentinal hypersensitivity: A comparative clinical evaluation of CPP-ACP F, sodium fluoride, propolis, and placebo

Madhavan, Souparna; Nayak, Moksha; Shenoy, Amarnath; Shetty, Rajesh; Prasad, Krishna

doi:10.4103/0972-0707.101882

Cited by 41 publications

(36 citation statements)

References 11 publications

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“…Restrepo et al and Ozgul et al reported the reduction of dental hypersensitivity in MIH‐affected teeth after application of fluoride varnish. These results are similar to those found by other authors in patients without MIH, who reported a decrease in dental hypersensitivity after the use of fluoride varnishes. Thus, fluoride varnish treatments may be considered a therapeutic option in cases of MIH‐related dental hypersensitivity.…”

Section: Discussionsupporting

confidence: 92%

Dental hypomineralization treatment: A systematic review

Coelho

Mata²,

Lino

et al. 2018

J Esthet Restor Dent

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Introduction Defects in the maturation stage of amelogenesis result in a normal volume of enamel but insufficient mineralization, called hypomineralization. Molar‐incisor hypomineralization (MIH), amelogenesis imperfecta and dental fluorosis (DF) are examples of such defects. Objective To evaluate the effectiveness of the treatments applied to the different forms of dental hypomineralization. Materials and Methods PubMed, Scopus, Cochrane Library, Web of Science, and Embase were screened. The research was limited to studies published in English, Spanish, and Portuguese, until May 30, 2018. The research question was formulated following the Population, Intervention, Comparison, Outcome strategy. The quality of the methodology of each article was evaluated employing the Cochrane Handbook for Systematic Reviews. Results From the initial research, 7895 references were obtained, of which 33 were included in the systematic review. The following treatments were reported: desensitizing and remineralizing products, resin infiltration, restorations, fissure sealants, tooth bleaching, enamel microabrasion and calcium, and vitamins supplements. Conclusions Although the results are suggestive, there is a clear need for a greater uniformity of the methodologies, thus allowing for the development of clinical guidelines. Nevertheless, it was possible to identify several effective treatments for teeth with MIH (arginine pastes or fluoride varnishes) and DF (tooth bleaching and/or enamel microabrasion). Clinical Significance Because MIH, amelogenesis imperfecta, and DF are commonly seen in dental daily practice, it is extremely important to analyze the literature regarding its treatment.

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Section: Discussionsupporting

confidence: 92%

Dental hypomineralization treatment: A systematic review

Coelho

Mata²,

Lino

et al. 2018

J Esthet Restor Dent

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“…The present results agree with other clinical studies in which the application of concentrated fluoride to exposed buccal dentin surfaces was effective in reducing hypersensitivity, as demonstrated by the increased resistance of dentin to decalcification and by the precipitation of calcium fluoride crystals in exposed dentinal tubules (14,16). However, Umberto et al (14) observed a greater efficacy of GaAlAs laser radiation when compared to NaF gel.…”

Section: Discussionsupporting

confidence: 63%

Clinical Efficacy of Fluoride Varnish and Low-Level Laser Radiation in Treating Dentin Hypersensitivity

et al. 2016

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The objective of this study was to compare the efficacy of fluoride varnish (Fluorniz®) and irradiation with a gallium-arsenide-aluminum diode laser in the treatment of cervical dentin hypersensitivity. Cervical dentin hypersensitivity (CDH) is a painful condition that is highly prevalent in the world's adult population, with one in six patients presenting this symptom. Eighty-six teeth were divided into two groups: Group 1, teeth treated with Fluorniz; Group 2, teeth irradiated with a GaAlAs laser at a 4 J/cm 2 dose. The two treatments were applied to the buccal cervical region in four sessions, at intervals of 72 to 96 h. The response of the patient to tactile and thermal-evaporative stimuli was rated on a visual analog scale. The results showed a reduction of hypersensitivity in response to tactile and thermal-evaporative stimulation at the end of treatment in both groups.In conclusion, short-term treatment with Fluorniz was found to be more effective than low-level laser radiation in reducing cervical dentin hypersensitivity.

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“…The high calcium availability provided by CLP, a novel remineralization agent, was attributed to its high solubility and calcium stabilization by random formation of metastable complexes of calcium ions with lactate and phosphate ions. Currently, remineralizing agents like NovaMin™ (bioactive glass containing calcium sodium phosphosilicate) [27,28], Recaldent™ (CPP-ACP casein phosphopeptide-amorphous calcium phosphate) [27,29], Enamelon ® (containing stannous fluoride along with calcium and phosphate ions) [30] were utilized as desensitizing agents. Analogous mechanism to these remineralizing agents is expected to provide the same relief to DH as CLP pastes.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste

Yang

Lee

et al. 2017

Materials

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Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey’s test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 µm to 2.62 ± 0.42 µm right after treatment, further decreasing to 1.71 ± 0.45 µm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion.

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Dentinal hypersensitivity: A comparative clinical evaluation of CPP-ACP F, sodium fluoride, propolis, and placebo

Cited by 41 publications

References 11 publications

Dental hypomineralization treatment: A systematic review

Dental hypomineralization treatment: A systematic review

Clinical Efficacy of Fluoride Varnish and Low-Level Laser Radiation in Treating Dentin Hypersensitivity

In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste

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