Dentinogenic ghost cell tumor: A bibliometric review of literature

Abstract

Oral lichen planus and oral lichenoid mucositis are the two most common lichenoid lesions of the oral cavity. Oral lichen planus is classified as a potentially malignant condition by the World Health Organization, and lichenoid mucositis has also been shown to have malignant potential. However, some argue that lichen planus or lichenoid mucositis is only premalignant when dysplasia has developed in these lesions and that many cases of lichen planus or lichenoid mucositis with cancer development were in fact either a lichenoid lesion with dysplasia or a primary dysplasia misdiagnosed as oral lichen planus or lichenoid mucositis due to the coexistence of lichenoid features. Here, we summarize what is known about the risk of malignant transformation of these lesions and discuss the ongoing controversies surrounding the diagnostic criteria.

Dentinogenic ghost cell tumor – Case report of a rare entity

“…Epidemiologically, it occurs more frequently in males, over a wide age range. The peak incidence is not yet consensual, however most studies point to an interval between the fourth and sixth decades [ 2 , 5 ], like the patient in our case.…”

“…From a clinical point of view, most patients present unspecific symptoms, most frequently progressive swelling and pain caused by cortical bone expansion. There are also many asymptomatic cases described [ 2 , 5 ].…”

“…Long-term surveillance is recommended due to high rate of recurrence and the possibility of malignant transformation [ 1 , 2 ]. In our case, a close clinical and radiological surveillance is being done, and 10 months after surgery there are no signs of local recurrence.…”

“…Dentinogenic ghost cell tumor (DGCT) is a benign neoplasm, locally invasive, classified as a mixed epithelial and mesenchymal odontogenic tumor in the latest edition of the World Health Organization Classification of Head and Neck Tumors [ 1 ], with about 60 cases described in the literature [ 2 ].…”

Etiology, management of ptosis in working age group and its surgical outcome – A prospective study

“…5 DGCT is extremely rare solid, neoplastic variant of COC, with about 60 cases described in the literature. 6 It can be central/intraosseous or peripheral/extraosseous. The central DGCT having a more aggressive behavior.…”