Dentinogenic ghost cell tumor – A case report and review of literature

Bussari, Smita; Thakur, Samantha M; Koshy, Ajit V; Shah, Amisha A

doi:10.4103/jomfp.jomfp_123_18

Cited by 9 publications

(11 citation statements)

References 11 publications

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“…The result culminated in 1992 with WHO naming the entity as neoplastic, irrespective of its cystic nature. In 2006, dentinogenic ghost cell tumor (DGCT) was the name given to solid variants as suggested by Praetorius et al [ 1 , 2 , 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…In instances, they undergo calcifications as in our case. Dentin expressed can be a tubular structure similar to normal dentin or have an appearance of an eosinophilic irregular mass [ 1 ]. Our case showed the presence of the classic features of ghost cells along with recognizable dentin.…”

Section: Discussionmentioning

confidence: 99%

“…The presentation though might be well contained or restricted. It can behave subtly, or actively as an aggressive tumor with high recurrence [ 1 , 10 , 11 ]. This calls for an aggressive line of treatment selection and free margins [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…Gorlin et al first identified and described COC as an entity of odontogenic origin [ 1 ]. He elucidated the histomorphological cellular features displayed by COC, both cystic and tumor counterparts [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…He elucidated the histomorphological cellular features displayed by COC, both cystic and tumor counterparts [ 2 ]. Reporting of more cases with variations led to contemplate a dualistic concept with emergence of names like dentinogenic ghost cell tumor (DGCT) with cystic and solid patterns [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

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Variations in Aggressive and Indolent Behaviour of Central Dentinogenic Ghost Cell Tumor

Bavle

Sudhakara

Makarla

et al. 2020

Case Reports in Dentistry

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Among the aggressive odontogenic tumors, a few tumors generally ameloblastomas, carry a connotation of being aggressive. But, a rare tumor like central dentinogenic ghost cell tumor (DGCT) can be equally aggressive with a propensity for recurrence. The two cases discussed in this article are divergent in behaviour with features such as presentation, seen in early decades as central intraosseous tumors in the maxilla and mandible. The first case describes an aggressive DGCT, associated with impacted tooth and odontome which showed recurrence into a large solid tumor within a year. The second case arose in accordance with a partially erupted molar which was comparatively innocuous and less aggressive. Both the cases exhibited classic histopathological features. These two unconventional cases of DGCT with a follow-up are being reported here to highlight the variation in behaviour and presentation and also to understand the aggressive nature of the tumor.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Variations in Aggressive and Indolent Behaviour of Central Dentinogenic Ghost Cell Tumor

Bavle

Sudhakara

Makarla

et al. 2020

Case Reports in Dentistry

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Pigmented dentinogenic ghost cell tumor: a unique case report and a review of the literature

Mohamed,

Yousif,

Elbashir

et al. 2024

Virchows Arch

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Central dentinogenic ghost cell tumor of the maxilla: a case report with new imaging findings and review of the literature

Yoshida,

Takeshita,

Kawazu

et al. 2024

Oral Radiol

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A dentinogenic ghost cell tumor (DGCT) is a rare benign odontogenic tumor that commonly shows characteristics of solid proliferation and has a relatively high risk of recurrence after surgical treatment. We herein report a case of a central DGCT that occurred in the maxilla and resulted in bone expansion. This study highlights new imaging findings (particularly magnetic resonance imaging) along with histopathological observations. In addition, we conducted a review of the existing literature on this rare tumor. A 37-year-old man developed swelling around the right cheek. A benign odontogenic tumor such as ameloblastoma was suspected based on the imaging examination findings (including bone expansion and the internal characteristics of the tumor) on panoramic imaging, computed tomography, and magnetic resonance imaging. The lesion was surgically excised from the right maxilla. Postoperative histopathological examination led to a definitive diagnosis of central DGCT. The tumor comprised epithelial neoplastic islands, resembling ameloblastoma, inside tight fibroconnective tissue; masses of ghost cells and formation of dentin were also observed. We had suspected that the minute high-density region around the molars on the imaging examinations represented alveolar bone change; however, it represented dentin formation. This led to difficulty diagnosing the lesion. Although DGCT may present characteristic findings on imaging examinations, its occurrence is infrequent, and in some cases, the findings may include the presence or absence of an impacted tooth without obvious calcification. The present case suggests that we should consider the possibility of an odontogenic tumor with calcification when high-density structures are observed inside the lesion.

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Dentinogenic ghost cell tumor – A case report and review of literature

Cited by 9 publications

References 11 publications

Variations in Aggressive and Indolent Behaviour of Central Dentinogenic Ghost Cell Tumor

Variations in Aggressive and Indolent Behaviour of Central Dentinogenic Ghost Cell Tumor

Pigmented dentinogenic ghost cell tumor: a unique case report and a review of the literature

Central dentinogenic ghost cell tumor of the maxilla: a case report with new imaging findings and review of the literature

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