Dependence of third-harmonic generation on melanin concentration in solution

Su, Tung Yu; Liao, Chien Sheng; Yang, Chih Yuan; Zhuo, Zong Yan; Chen, Szu Yu; Chu, Shi Wei

doi:10.1117/12.872837

Cited by 1 publication

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“…Compared with fluorescence microscopy, harmonic generation microscopy can image cells and tissue structures without labeling, thus providing complementary information on the microenvironment. Various biomaterials, such as collagen, spindle fibers, bones, hemoglobin, melanin, and lipid bodies, have either SHG or THG contrasts in harmonic generation microscopy ( 50 – 55 ). These label-free features have been widely used to visualize the cellular and tissue structures in muscles, the skin, the brain, and the oral mucosa ( 56 – 59 ).…”

Section: Optical Imaging Techniquesmentioning

confidence: 99%

Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques

Liu

2018

Front. Immunol.

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Macrophages are an important component of host defense and inflammation and play a pivotal role in immune regulation, tissue remodeling, and metabolic regulation. Since macrophages are ubiquitous in human bodies and have versatile physiological functions, they are involved in virtually every disease, including cancer, diabetes, multiple sclerosis, and atherosclerosis. Molecular biological and histological methods have provided critical information on macrophage biology. However, many in vivo dynamic behaviors of macrophages are poorly understood and yet to be discovered. A better understanding of macrophage functions and dynamics in pathogenesis will open new opportunities for better diagnosis, prognostic assessment, and therapeutic intervention. In this article, we will review the advances in macrophage tracking and analysis with in vivo optical imaging in the context of different diseases. Moreover, this review will cover the challenges and solutions for optical imaging techniques during macrophage intravital imaging.

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Section: Optical Imaging Techniquesmentioning

confidence: 99%

Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques

Liu

2018

Front. Immunol.

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Dependence of third-harmonic generation on melanin concentration in solution

Cited by 1 publication

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Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques

Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques

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