2000
DOI: 10.1097/00006842-200003000-00011
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Depression and Anxiety As Predictors of Outcome After Myocardial Infarction

Abstract: Subjects who are distressed in the hospital are at high risk of adverse psychological and quality-of-life outcomes during the ensuing year. Our findings strengthen the argument for in-hospital identification and treatment of patients with depression and anxiety after myocardial infarction.

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Cited by 413 publications
(308 citation statements)
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“…Herrmann and colleagues showed that the HADS-D was associated with higher mortality in multivariate analysis in cardiology patients referred for exercise testing [27]. Mayou et al found that AMI patients with elevated HADS scores did not show higher risk of mortality [13], however these researchers used a composite of both anxiety and depression scales, and this may explain these negative findings.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Herrmann and colleagues showed that the HADS-D was associated with higher mortality in multivariate analysis in cardiology patients referred for exercise testing [27]. Mayou et al found that AMI patients with elevated HADS scores did not show higher risk of mortality [13], however these researchers used a composite of both anxiety and depression scales, and this may explain these negative findings.…”
Section: Discussionmentioning
confidence: 99%
“…Early diagnosis and active management of depression may improve cardiac morbidity and mortality [13]. A recent review found that between 8 to 45% of patients who have suffered an AMI exhibit symptoms of major depression [5].…”
Section: Introductionmentioning
confidence: 99%
“…Numerous studies have found that symptoms of depression are related to increased risk of mortality following acute myocardial infarction (AMI) after controlling for demographic and disease severity variables [1][2][3][4], although not all studies have reported a significant association [5,6]. Several recent systematic reviews or meta-analyses of the independent association between post-AMI depression and mortality have concluded that unambiguous conclusions could not be reached because of incomplete control for confounding [7][8][9].…”
Section: Introductionmentioning
confidence: 99%
“…Tra i pazienti coronaropatici, quelli affetti da depressione maggiore presentano, rispetto ai non depressi, una piu elevata prevalenza di aritmie ventricolari e vanno incontro piu frequentemente a reinfarto, interventi di cardiochirurgia o decesso entro un anno dall'esordio del disturbo affettivo (Carney et al, 1988;. Oltre alia possibilita di gravi complicanze cardiologiche, la depressione incrementa il rischio di morte improvvisa anche nei depressi con anamnesi negativa per patologie cardiovascolari (Roose et al, 1991;Mayou et al, 2000).…”
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“…Secondo Carney et al (1997), nell'ambito della patologia coronarica, solamente il 20% dei casi di depressione vengono riconosciuti e, fatto ancor piu grave, soltanto il 10% delle depressioni maggiori viene adeguatamente trattato, con gravi conseguenze per il paziente (aggravamento dei sintomi della patologia organica, maggiore disabilita funzionale e sociale, peggioramento della qualita di vita, ridotta adesione ai programmi volti alia modificazione di stili comportamentali disadattativi, ai trattamenti ed ai controlli medici programmati, peggioramento prognostico, incremento di mortalita), ma anche sul piano socio-economico (prolungamento dei tempi di ospedalizzazione, maggior numero di ricoveri ospedalieri, incremento dei costi socio-economici) (Cassem, 1995;Frasure-Smith etal., 2000;Mayou et al, 2000). Al contrario, il trattamento della depressione puo contribuire notevolmente a migliorare la qualita di vita e, probabilmente, anche la sopravvivenza dei pazienti con malattia cardiovascolare (Musselmanef a/., 1998).…”
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