Depression and epilepsy: comorbidities, pathogenesis, principles of therapy

Rider, Flora; Даниленко, О. А.; Grishkina, M. N.; Kustov, Georgii; Akzhigitov, R. G.; Лебедева, А. В.; Guekht, Alla

doi:10.17116/jnevro20161169219-24

Cited by 11 publications

(2 citation statements)

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“…Key words: epilepsy, organic depression, psychogenic depression, endogenous depression, interictal period, emotional state, anxiety * Епілепсія являє собою захворювання головного мозку, що визначається стійкою схильністю до генерації епілептичних приступів, окрім яких невід'ємною частиною захворювання є також непароксизмальні прояви, що мають у своєму складі психопатологічні порушення [1]. Однак психопатологічні порушення найчастіше залишаються поза увагою спеціалістів та їх не завжди адекватно класифікують завдяки їх схожості з проявами самих приступів або побічними проявами протиепілептичної терапії [2][3][4]. Серед психопатологічних порушень при епілепсії одними з найбільш поширених є депресивні розлади, які, за даними різних авторів, спостерігаються в діапазоні від 10 до 80 % випадків [5].…”

Section: I Kharytonov Analysis Of the Emotional State Of Patientsunclassified

Analysis of the emotional state of patients with epilepsy and depression in interactal period

Kharytonov¹

2019

UVP

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The paper presents the results of the analysis of the emotional state of patients with epilepsy and depressions in the interictal period. Was analyzed the entire spectrum of aff ective manifestations (positive and negative emotional reactions), and were separately investigated the structural features of anxiety. It has been established that in the structure of the emotional state of patients with epilepsy, both with depressions and without, is noted the presence of negative aff ectivity in the form of reactions of tension, anxiety, anger, and frustration. The specifi c character of the emotional state of patients with epilepsy with depressions lies not so much in the representation of specifi c negative emotional states, but in the range of their severity. The emotional state of patients with epilepsy and depressions is represented by extremely negative emotional reactions, among which the most pronounced and characteristic of all forms of depression is the feeling of sadness. The specifics of the emotional state are determined depending on the form of depression: against the background of the state of sadness, with organic depression in the aff ective state, dominates the feeling of fatigue; with psychogenic — tension and anxiety; with endogenous — self-deprecation. Were distinguished the structural features of anxiety in patients with various forms of depression, was noted its high level in psychogenic depressions.

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Section: I Kharytonov Analysis Of the Emotional State Of Patientsunclassified

Analysis of the emotional state of patients with epilepsy and depression in interactal period

Kharytonov¹

2019

UVP

View full text Add to dashboard Cite

show abstract

“…Increases in Stress Levels and the Problem of Treatment Adherence. Epilepsy patients not infrequently have comorbid pathologies, including psychiatric [20,[22][23][24], and they have a greater tendency to form suicidal ideations and a greater frequency of suicide attempts [25]. In the Russian population, the number of epilepsy patients with depression, affective-anxiety, and other disorders is very high, though as shown by our observations, a majority of these patients avoid seeing a psychiatrist [22].…”

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confidence: 99%