Depression and low physical activity are related to sarcopenia in hemodialysis: a single-center study

Yuenyongchaiwat, Kornanong; Jongritthiporn, Sasikan; Somsamarn, Kasarn; Sukkho, Oranat; Pairojkittrakul, Sasipim; Traitanon, Opas

doi:10.7717/peerj.11695

Cited by 20 publications

(15 citation statements)

References 27 publications

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“…The studies were published between 2014 and 2022 and varied in sample size (33 to 645 patients). Among the included studies, twenty-one studies were conducted in Asian countries (China, Iran, Japan, Korea, Taiwan, Thailand, and Turkey) [ 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 ], nine in European countries (France, Sweden, Spain, and United Kingdom) [ 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ], eight in South American countries (Brazil and Argentina) [ 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 ], two in the USA [ 57 , 58 ], and the remaining one in Australia [ 59 ]. These studies yielded a total sample of five continents (Asia: 45.6%, Europe: 25.9%, North America: 14.3%, South America: 13.7%, and Australia: 0.5%).…”

Section: Resultsmentioning

confidence: 99%

“…These studies yielded a total sample of five continents (Asia: 45.6%, Europe: 25.9%, North America: 14.3%, South America: 13.7%, and Australia: 0.5%). Thirty-one studies [ 19 , 22 , 23 , 24 , 25 , 26 , 27 , 29 , 30 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 43 , 44 , 46 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ] were conducted in HD population, seven studies [ 20 , 21 , 28 , 31 , 32 , 42 , 47 ] were performed in PD population, and three studies [ 24 , 33 , 59 ] were carried out in mixed populations (both HD and PD). Of the included patients, the mean age was 62.3 years, 61.4% were male, and 38.6% had diabetes mellitus as a comorbidity with a mean dialysis vintage of 52.4 months.…”

Section: Resultsmentioning

confidence: 99%

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Prevalence of Sarcopenia and Its Impact on Cardiovascular Events and Mortality among Dialysis Patients: A Systematic Review and Meta-Analysis

et al. 2022

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Sarcopenia in end-stage kidney disease patients requiring dialysis is a frequent complication but remains an under-recognized problem. This meta-analysis was conducted to determine the prevalence of sarcopenia and explored its impacts on clinical outcomes, especially cardiovascular events, and mortality in dialysis patients. The eligible studies were searched from PubMed, Scopus, and Cochrane Central Register of Controlled trials up to 31 March 2022. We included studies that reported the interested outcomes, and the random-effects model was used for analysis. Forty-one studies with 7576 patients were included. The pooled prevalence of sarcopenia in dialysis patients was 25.6% (95% CI 22.1 to 29.4%). Sarcopenia was significantly associated with higher mortality risk (adjusted OR 1.83 (95% CI 1.40 to 2.39)) and cardiovascular events (adjusted OR 3.80 (95% CI 1.79 to 8.09)). Additionally, both low muscle mass and low muscle strength were independently related to increased mortality risk in dialysis patients (OR 1.71; 95% CI (1.20 to 2.44), OR 2.15 (95% CI 1.51 to 3.07)), respectively. This meta-analysis revealed that sarcopenia was highly prevalent among dialysis patients and shown to be an important predictor of cardiovascular events and mortality. Future intervention research to alleviate this disease burden in dialysis patients is needed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Prevalence of Sarcopenia and Its Impact on Cardiovascular Events and Mortality among Dialysis Patients: A Systematic Review and Meta-Analysis

et al. 2022

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“…Patients on hemodialysis have a higher risk of depression when their capacity to engage in physical activity is reduced [ 5 ]. This may be related to physical burdens, quality of life, and role loss of such patients because of their chronic disease [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Common comorbidities include hypertension, diabetes, and cardiovascular diseases [ 3 ]. When a patient’s comorbidity index score increases during their hemodialysis treatment, they are more likely to experience reduced physical function and activity, increased negative emotions, and increased disease severity [ 4 , 5 ]. Patients on hemodialysis with a greater number of comorbidities have been reported to have more severe depression, higher levels of anxiety [ 6 ], and higher fatigue scores [ 7 ] than those with fewer comorbidities.…”

Section: Introductionmentioning

confidence: 99%

Correlation between Physical Activity and Psychological Distress in Patients Receiving Hemodialysis with Comorbidities: A Cross-Sectional Study

Hsu

Tzeng

2022

IJERPH

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Comorbidities cause psychological distress to patients on hemodialysis and cause their physical function to deteriorate. This study aims to examine whether physical patterns are associated with anxiety, depression and fatigue among patients with and without comorbidities who are on hemodialysis. To this end, a cross-sectional survey was administered to 120 patients on hemodialysis. Data were collected using the International Physical Activity Questionnaire—Short Form, Beck Depression Inventory—Second Edition, Beck Anxiety Inventory, and Brief Fatigue Inventory—Taiwan Version. An independent sample t test and generalized linear model analyses were conducted. The results revealed that patients with comorbidities exhibited more severe levels of depression (p < 0.001), anxiety (p < 0.001), and fatigue (p = 0.010) than patients without comorbidities. Additionally, patients on hemodialysis with a high physical activity level (≥600 metabolic equivalent of task per min/week) exhibited less depression (B = −4.03; p < 0.001; 95% confidence interval [CI] = −6.04, −2.03) and anxiety (B = −2.64; p = 0.002; 95% CI = −4.27, −1.00) severity than those with a low physical activity level; those who engaged in weekly physical activities exhibited less fatigue severity (B = −1.17; p = 0.001; 95% CI = −1.84, −0.49) and fatigue interference (B = −0.61; p = 0.015; 95% CI = −1.10, −0.12). For patients on hemodialysis, having comorbidities was correlated with more severe levels of depression, anxiety, and fatigue. Weekly moderate-intensity physical activities were revealed to be correlated with less severity levels of depression, anxiety, and fatigue. The study findings aid the development of interventions for promoting physical activity among patients on hemodialysis to prevent the exacerbation of complications caused by comorbidities and psychological distress.

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“…Several previous studies, which explored sarcopenia and depression indicated that individuals with sarcopenia had a high depression score or depressive symptoms. 22,[31][32][33] In the present study, it should be noted that low response rate to the PHQ-9 items in HF was observed (2.13AE3.14 scores), which may have limited the ability to determine the increased risk for scoring high on sarcopenia.…”

Section: P-value P-valuementioning

confidence: 56%

Association between depression and sarcopenia in patients with heart failure

2022

Self Cite

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Background: Prevalence of heart failure has been increasing worldwide. Decreased muscle mass, poor physical activity, and reduced physical performance or muscle strength might lead to sarcopenia among heart failure patients and therefore lead to low cardiac output, and vice versa. Symptoms of depression are also common mental health problems in heart failure. However, little is known about the prevalence of depressive symptoms in heart failure patients with sarcopenia and the relationship with its. This study aimed to explore the prevalence of and relationship between sarcopenia and depressive symptoms in heart failure patients. Methods: A cross-sectional study comprised of 150 participants aged 35 years or older. Sarcopenia and no sarcopenia were classified by using the Asian Working Group for Sarcopenia 2019 criteria. Physical performance, muscle strength, and skeletal muscle mass were examined. Symptoms of depression were assessed through utilization of the validated Thai version of Patient Health Questionnaire 9. Results: The prevalence of sarcopenia was 18.67% and depression was 5.33% in heart failure patients. In addition, the prevalence of depression in heart failure patients with sarcopenia were 3.57%. The relationship was observed based on depression scores and New York Heart Association functional classification (r = 0.319, p<.001). Furthermore, heart failure patients with low New York Heart Association functional class had high depression scores (p<.001). However, no significant differences between depression scores and sarcopenia in heart failure patients were identified. Conclusions: Prevalence of sarcopenia in heart failure patients was 18.67% and only 5.33% exhibited depressive symptoms. Only 3.57% exhibited both depression and sarcopenia. Additionally, New York Heart Association functional classification was related to depression.

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Depression and low physical activity are related to sarcopenia in hemodialysis: a single-center study

Cited by 20 publications

References 27 publications

Prevalence of Sarcopenia and Its Impact on Cardiovascular Events and Mortality among Dialysis Patients: A Systematic Review and Meta-Analysis

Prevalence of Sarcopenia and Its Impact on Cardiovascular Events and Mortality among Dialysis Patients: A Systematic Review and Meta-Analysis

Correlation between Physical Activity and Psychological Distress in Patients Receiving Hemodialysis with Comorbidities: A Cross-Sectional Study

Association between depression and sarcopenia in patients with heart failure

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