Depression and marital status determine the 10-year (2004–2014) prognosis in patients with acute coronary syndrome: The GREECS study

Notara, Venetia; Panagiotakos, Demosthenes B.; Papataxiarchis, Evagellos; Verdi, Μargarita; Michalopoulou, Moscho; Tsompanaki, Elena; Kogias, Yannis; Stravopodis, Petros; Papanagnou, George; Zombolos, Spyros; Stergiouli, Ifigenia; Mantas, Yannis; Pitsavos, Christos

doi:10.1080/08870446.2015.1034720

Cited by 21 publications

(11 citation statements)

References 33 publications

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“…CVD than those without depression [24]. The results of this study are consistent with those of several studies showing that depression and anxiety among people with other diseases predicted CVD [25][26][27].…”

Section: E P U B a H E A D O F P R I N Tsupporting

confidence: 92%

Associations of depression and anxiety with cardiovascular risk among people living with HIV/AIDS in Korea

et al. 2020

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OBJECTIVES As HIV/AIDS is becoming a chronic disease, the risk of developing cardiovascular disease (CVD) among people living with HIV/AIDS is rising. Anxiety and depression, which are common among people living with HIV/AIDS, have been linked with CVD. This study investigated the risk of CVD in people living with HIV/AIDS and explored the effects of depression and anxiety on CVD risk. METHODS Data were collected for 457 people enrolled in the Korea Cohort HIV/AIDS study after 2010. Framingham risk scores were calculated to quantify the 10-year risk of developing CVD. Depression and anxiety variables were re-coded as a single combined variable. Multivariable logistic regression analysis was performed, adjusting for age, body mass index, low-density lipoprotein (LDL) cholesterol, triglycerides (TG), duration of human immunodeficiency virus (HIV) positivity after entry into the cohort, and depression/anxiety. RESULTS Participants with both depression and anxiety were 2.28 times more likely than those with neither depression nor anxiety to have moderate/high-risk CVD risk. The 10-year risk of developing CVD was affected by LDL cholesterol, TG, age, and duration of HIV infection. LDL cholesterol and TG levels change according to the duration of HIV infection, and metabolic disorders affect the risk of CVD. Thus, a longer duration of HIV infection is associated with a higher risk of developing CVD. CONCLUSIONS Screenings for depression and anxiety need to be provided regularly to assess the severity of those symptoms. To help decrease their risk of developing CVD, people living with HIV/AIDS should be offered behavioral modification interventions aimed at developing healthy lifestyle habits.

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Section: E P U B a H E A D O F P R I N Tsupporting

confidence: 92%

Associations of depression and anxiety with cardiovascular risk among people living with HIV/AIDS in Korea

et al. 2020

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“…25 The general log-linear model also showed that there is an association between the variable marital status and MDD conditioned to gender. What can be inferred from this is that this association pertained to the unmarried and females, who, as aforementioned, showed a greater tendency to MDD than married persons and males.…”

Section: Discussionmentioning

confidence: 91%

Major Depression and Acute Coronary Syndrome-Related Factors

Figueiredo¹,

Silva²,

Pereira³

et al. 2017

Arquivos Brasileiros De Cardiologia

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BackgroundMajor Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS).ObjectiveTo assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of sociodemographic, lifestyle and clinical variables.MethodsObservational, descriptive, cross-sectional, case-series study conducted on patients hospitalized consecutively at the coronary units of three public hospitals in the city of Rio de Janeiro over a 24-month period. All participants answered a standardized questionnaire requesting sociodemographic, lifestyle and clinical data, as well as a structured diagnostic interview for the DSM-IV regarding ongoing major depressive episodes. A general log-linear model of multivariate analysis was employed to assess association and interdependence with a significance level of 5%.ResultsAnalysis of 356 patients (229 men), with an average and median age of 60 years (SD ± 11.42, 27-89). We found an MDD point prevalence of 23%, and a significant association between MDD and gender, marital status, sedentary lifestyle, Killip classification, and MDD history. Controlling for gender, we found a statistically significant association between MDD and gender, age ≤ 60 years, sedentary lifestyle and MDD history. The log-linear model identified the variables MDD history, gender, sedentary lifestyle, and age ≤ 60 years as having the greatest association with MDD.ConclusionDistinct approaches are required to diagnose and treat MDD in young women with ACS, history of MDD, sedentary lifestyle, and who are not in stable relationships.

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“…The GREECS study found similar associations, amplified by depression severity, between marital status and recurrent acute coronary syndrome in approximately 2000 patients. 26 Although some studies suggest that marital status affects cardiac rehabilitation programme attendance and physical activity in secondary prevention, 27,28 possible underlying effects on the association as well as causality remain unclear. The gender interaction observed in the current study for the association between unmarried status and the outcome may indicate that men, to a larger extent than women, are dependent on a spouse to adhere to treatment.…”

Section: Discussionmentioning

confidence: 99%

Socioeconomic status predicts second cardiovascular event in 29,226 survivors of a first myocardial infarction

Ohm

Skoglund

Discacciati

et al. 2018

Eur J Prev Cardiolog

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Background Risk assessment post-myocardial infarction needs improvement, and risk factors derived from general populations apply differently in secondary prevention. The prediction of subsequent cardiovascular events post-myocardial infarction by socioeconomic status has previously been poorly studied. Design Swedish nationwide cohort study. Methods A total of 29,226 men and women (27%), 40-76 years of age, registered at the standardised one year revisit after a first myocardial infarction in the secondary prevention quality registry of SWEDEHEART 2006-2014. Personal-level data on socioeconomic status measured by disposable income and educational level, marital status, and the primary endpoint, first recurrent event of atherosclerotic cardiovascular disease, defined as non-fatal myocardial infarction or coronary heart disease death or fatal or non-fatal stroke were obtained from linked national registries. Results During the mean 4.1-year follow-up, 2284 (7.8%) first recurrent manifestations of atherosclerotic cardiovascular disease occurred. Both socioeconomic status indicators and marital status were associated with the primary endpoint in multivariable Cox regression models. In a comprehensively adjusted model, including secondary preventive treatment, the hazard ratio for the highest versus lowest quintile of disposable income was 0.73 (95% confidence interval 0.62-0.83). The association between disposable income and first recurrent manifestation of atherosclerotic cardiovascular disease was stronger in men as was the risk associated with being unmarried (tests for interaction P < 0.05). Conclusions Among one year survivors of a first myocardial infarction, first recurrent manifestation of atherosclerotic cardiovascular disease was predicted by disposable income, level of education and marital status. The association between disposable income and first recurrent manifestation of atherosclerotic cardiovascular disease was independent of secondary preventive treatment but further study on causal pathways is needed.

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Depression and marital status determine the 10-year (2004–2014) prognosis in patients with acute coronary syndrome: The GREECS study

Abstract: The present study highlights the important role of depression in the context of marital relationships among ACS patients. Secondary public health care intervention programmes are needed to improve patient outcomes and minimise disease burden in clinical and community setting.

Cited by 21 publications

References 33 publications

Associations of depression and anxiety with cardiovascular risk among people living with HIV/AIDS in Korea

Associations of depression and anxiety with cardiovascular risk among people living with HIV/AIDS in Korea

Major Depression and Acute Coronary Syndrome-Related Factors

Socioeconomic status predicts second cardiovascular event in 29,226 survivors of a first myocardial infarction

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