Depression and suicidal behavior among adolescents living with HIV in Botswana: a cross-sectional study

Olashore, Anthony A.; Paruk, Saeeda; Tshume, Ontibile; Chiliza, Bonginkosi

doi:10.1186/s13034-022-00492-9

Cited by 12 publications

(10 citation statements)

References 39 publications

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“…Correspondingly, most research has focused on Eastern and Southern Africa. A cross-sectional study in Botswana, which ranked among the top four countries most affected by HIV, reported the prevalence of depression among adolescents living with HIV were 23% ( Olashore et al, 2022 ), which is consistent with the rate (24–27%) in the systematic review in sub-Saharan ( Dessauvagie et al, 2020 ). West et al (2019) found that the majority of HIV-infected adolescents were infected perinatally, and the adolescents who receive earlier and higher social support were less likely to have mental health symptoms ( West et al, 2019 ).…”

Section: Discussionsupporting

confidence: 70%

Global trends in depression among patients living with HIV: A bibliometric analysis

Zhang

Hao

et al. 2023

Front. Psychol.

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BackgroundHuman immunodeficiency virus (HIV) related depression has seriously affected the quality of life and treatment outcomes of patients living with HIV (PLWH), which has become a hot topic in recent years. This study aims to discover the main keywords, predict frontier topics, and give meaningful suggestions for researchers by bibliometric analysis.MethodsPublications between 1999 and 2022 on depression in HIV/AIDS were searched in the Web of Science core collection. Microsoft Excel 2010 and VOSviewer were utilized to key contributors (e.g., authors, journals, institutions, and countries). VOSviewer and CiteSpace were used to analyze the knowledge evolution, collaborative maps, hot topics, and keywords trends in this field.ResultsIn total, 8,190 publications were included in the final analysis. From 1999 to 2021, the number of published articles roughly presents a steadily increasing trend. The United States, South Africa, and the United Kingdom were three key contributing countries/regions to this field. University Calif San Francisco (United States), University Calif Los Angeles (United States), and Johns Hopkins University (United States) were three key contributing institutions. Safren, Steven A. was the most productive and highest cited author. AIDS Care was the top prolific journal. Antiretroviral therapy and adherence, men has sex with men, mental health, substance abuse, stigma, and Sub-Saharan Africa were the central topics regarding the depression-related research in HIV/AIDS.ConclusionThis bibliometric analysis reported the publication trend, major contributing countries/regions, institutions, authors, journals and mapped the knowledge network of depression-related research on HIV/AIDS. In this field, topics such as “adherence,” “mental health,” “substance abuse,” “stigma,” “men who have sex with men” and “South Africa” have attracted considerable attention.

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Section: Discussionsupporting

confidence: 70%

Global trends in depression among patients living with HIV: A bibliometric analysis

Zhang

Hao

et al. 2023

Front. Psychol.

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“…There were three main responses: ‘still struggling,’ ‘has accepted status,’ and ‘do not know my status.’ However, the last response was excluded from the analysis. A more detailed description of this has been reported in a previous manuscript [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

Psychiatric disorders in adolescents living with HIV in Botswana

et al. 2023

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Background As children living with HIV transition from adolescence into adulthood, they face a considerable burden of psychiatric disorders (PDs) which may vary between the perinatally and behaviorally infected. The knowledge of the pattern of these PDs in relation to the varying needs of the adolescents living with HIV (ALWHIV) is unclear but necessary for maximizing their linkage to care and improving their quality of life in Botswana. Aim To determine the pattern of PDs in ALWHIV in Botswana; to compare and explore the differences in the pattern and their associated factors between congenitally infected adolescents (CIAs) and behaviorally infected adolescents (BIAs). Methods A cross-sectional survey of 622 ALWHIV (399 CIA and 223 BIA) with the Mini International Neuropsychiatric Interview-Kid Screen. Results The participants' mean age (SD) was 17.71 (1.60) years, with more males (54%), of whom 52.9% had at least one PD, with depression (23.6%) and generalised anxiety disorder (18.0%) being the most prevalent. The externalising disorders were associated with being CIA (OR = 3.99; 95% CI:1.87–8.54), male gender (OR = 3.93; 95% CI:2.02–7.64), and a viral load of 400 and above copies (OR = 3.53; 95%CI:1.92–6.48). Internalising disorders were associated with being BIA (OR = 3.64; 95%; CI: 2.39–5.56), females (OR = 2.59; 95% CI:1.75–3.83), poor counselling (OR = 2.23; 95% CI: 1.42–3.51) and struggling to accept HIV status (OR = 1.73; 95% CI:1.14–2.62). Conclusions Depression and anxiety disorders were the most prevalent PDs in ALWHIV, who differed in psychiatric presentations, the BIAs being more likely to present with internalizing disorders, while the CIAs had more externalizing disorders. Due to the varying needs of ALWHIV, individualized management plans that consider gender, mode of infection, and other psycho-social needs, should be further studied and encouraged.

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“…This was a randomized, controlled trial to assess the psychological intervention program in ALWHIV, aged 15–19, who attend medical clinics at Botswana Baylor Children's Clinical Centre of Excellence (BBCCCE). An earlier manuscript has reported details regarding the study site and clinic activities [ 17 ].…”

Section: Methodsmentioning

confidence: 99%

The effectiveness of psychoeducation and problem-solving on depression and treatment adherence in adolescents living with HIV in Botswana: an exploratory clinical trial

Olashore

Paruk

Ogunwale

et al. 2023

Child Adolesc Psychiatry Ment Health

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Background This study aimed to explore the effectiveness of psychological interventions (PI): psychoeducation, problem-solving, and rehearsal strategies on depression and adherence in HIV-infected adolescents in Botswana. Methods Fifty adolescents living with HIV were randomized into control (n = 25) and intervention groups (n = 25), the latter being exposed to five weeks of PI sessions. The PHQ-9 and visual analog scale (VAS) were used to measure the outcomes: depression and adherence at pre-intervention, 5- and 24 weeks post-intervention. Results The participants’ mean age (SD) was 17.38 years (1.1), the two groups being similar in socio-demographic variables: gender (χ2 = 2.22; p = 0.135) and age (U = 285, z = − 0.55, p = 0.579). The intervention group scored significantly lower on depressive symptoms (PHQ-9 [F (1,50) = 12.0, p = 0.001, ƞp2 = 0.20]) and higher on adherence score (VAS [F (1,50) = 13.5, p = 0.001, ƞp2 = 0.22]) than the control group after 5 weeks. The post-hoc analysis showed that the significant improvements in depressive symptoms (z = − 4.03, p < 0.01, r [effect size] = 0.88) and adherence (z = − 4.05, p < 0.01, r = 0.88) at post-test in the intervention group were maintained at 24 weeks. This project was registered with ClinicalTrials.gov (NCT05482217). Conclusion The 5-week PI showed promising effectiveness in addressing depression and adherence in adolescents living with HIV in Botswana.

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Depression and suicidal behavior among adolescents living with HIV in Botswana: a cross-sectional study

Cited by 12 publications

References 39 publications

Global trends in depression among patients living with HIV: A bibliometric analysis

Global trends in depression among patients living with HIV: A bibliometric analysis

Psychiatric disorders in adolescents living with HIV in Botswana

The effectiveness of psychoeducation and problem-solving on depression and treatment adherence in adolescents living with HIV in Botswana: an exploratory clinical trial

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