2018
DOI: 10.3233/jad-170778
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Depressive Symptoms Are Associated with Cognitive Function in the Elderly with Type 2 Diabetes

Abstract: Background:Type 2 diabetes (T2D) is a metabolic condition associated with poor clinical and cognitive outcomes including vascular disease, depressive symptoms, cognitive impairment, and dementia. In the general elderly population, depression has been consistently identified as a risk factor for cognitive impairment/decline. However, the association between depression and cognitive function in T2D has been understudied.Objective:We investigated the association between depression and cognitive function in a larg… Show more

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Cited by 15 publications
(19 citation statements)
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“…In addition, scholars suggest that diabetes‐specific emotional distress will affect patients’ moods, because the greater the emotional distress, the more the depressive symptoms that will arise (Koekkoek et al., 2015), and depressive symptoms have complex connections with cognitive fields, such as executive function, language and overall cognition (Birch et al., 2016; Guerrero‐Berroa et al., 2018; Vance et al., 2016).…”
Section: Discussionmentioning
confidence: 99%
“…In addition, scholars suggest that diabetes‐specific emotional distress will affect patients’ moods, because the greater the emotional distress, the more the depressive symptoms that will arise (Koekkoek et al., 2015), and depressive symptoms have complex connections with cognitive fields, such as executive function, language and overall cognition (Birch et al., 2016; Guerrero‐Berroa et al., 2018; Vance et al., 2016).…”
Section: Discussionmentioning
confidence: 99%
“…In this case, the study which provided the longest follow-up was selected. In total, 19 articles were included in this systematic review [12][13][14][15][16][17][18][32][33][34][35][36][37][38][39][40][41], of which 10 were eligible for meta-analyses [15][16][17][18]32,34,36,37]. Other results were reported qualitatively.…”
Section: Study Selectionmentioning
confidence: 99%
“…Regarding cognition, eight cross-sectional studies [32][33][34][35][36][37][38]42], two prospective cohort studies [12,14] and one retrospective cohort study [13] were included (Table 1). The research area was distributed among the United States [13,14,33,34,37], United Kingdom [12], Israel [32], Singapore [35], China [38,42] and Canada [14]. Four studies assessed both types of DM [13,35,37,38], the remaining six studies only assessed type 2 DM [12,14,[32][33][34]36,42].…”
Section: Study Characteristicsmentioning
confidence: 99%
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“…Depressed people with diabetes perform significantly worse on EF tasks. However, this correlation was not significant in a subsample of 715 participants taking antidepressants ( Guerrero-Berroa et al, 2018 ), suggesting that depression-mediated impairment in EF among patients with diabetes can be alleviated with antidepressant treatment.…”
Section: Factors Involved In Diabetes-related Ef Deficitsmentioning
confidence: 94%