Depressor effect on blood pressure and flow elicited by electroacupuncture in normal subjects

Lin, Chih Feng; Liao, Jiuan Miaw; Tsai, Shih Jei; Chiang, Ping Yen; Ting, Hua; Tang, Chih Yung; Lou, Kuo-Long; Hsieh, Li Chun; Wang, Den Wu; Lin, Tzer Bin

doi:10.1016/s1566-0702(03)00103-6

Cited by 17 publications

(11 citation statements)

References 16 publications

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“…As of May 2011, only six scientific articles concerning “arterial stiffness and acupuncture,” “wave reflection and acupuncture,” and “pulse wave velocity and acupuncture” could be found in the scientific literature [6, 19–23]. …”

Section: Discussionmentioning

confidence: 99%

Brain-Modulated Effects of Auricular Acupressure on the Regulation of Autonomic Function in Healthy Volunteers

Gao

Wang

Gaischek

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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Auricular acupuncture has been described in ancient China as well as Egypt, Greece, and Rome. At the end of the 1950s, ear acupuncture was further developed by the French physician Dr. Paul Nogier. The goal of this study was to develop a new system for ear acupressure (vibration stimulation) and to perform pilot investigations on the possible acute effects of vibration and manual ear acupressure on heart rate (HR), heart rate variability (HRV), pulse wave velocity (PWV), and the augmentation index (AIx) using new noninvasive recording methods. Investigations were performed in 14 healthy volunteers (mean age ± SD: 26.3 ± 4.3 years; 9 females, 5 males) before, during, and after acupressure vibration and manual acupressure stimulation at the “heart” auricular acupuncture point. The results showed a significant decrease in HR (P ≤ 0.001) and a significant increase in HRV total (P = 0.008) after manual ear acupressure. The PWV decreased markedly (yet insignificantly) whereas the AIx increased immediately after both methods of stimulation. The increase in the low-frequency band of HRV was mainly based on the intensification of the related mechanism of blood pressure regulation (10-s-rhythm). Further studies in Beijing using animal models and investigations in Graz using human subjects are already in progress.

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Section: Discussionmentioning

confidence: 99%

Brain-Modulated Effects of Auricular Acupressure on the Regulation of Autonomic Function in Healthy Volunteers

Gao

Wang

Gaischek

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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“…One study on electroacupuncture stimulation of the forearm, hence within the distribution of the lower cervical or upper thoracic spinal nerves, showed a reduction in blood pressure and an increase in HR. 40 The authors interpreted these results as indicating reduced sympathetic outflow to the peripheral vasculature, with reduced cardiac vagal output and therefore increased HR. Conversely, another study on conventional acupuncture, using a different forearm insertion point, showed decreased HR.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Thoracic Manipulation on Heart Rate Variability: A Controlled Crossover Trial

Budgell

Polus

2006

Journal of Manipulative and Physiological Therapeutics

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“…Most current research in this field uses continuous blood pressure monitors, such as Finometers, because they provide a real-time measurement that can be averaged over each interval of the experiment. MAP and CVR can then be accurately calculated from these measurements [66,81,112,126,156]. These systems are very expensive (~$25-30k, based on quotes obtained from ADInstruments and Finapres), however, and could not be purchased for this study.…”

Section: Discussionmentioning

confidence: 99%

“…In our pre-pilot work, the participant rested their arms on a pillow to ensure comfort and that pressure was evenly distributed across the forearm from the blood pressure cuff. Having the participant lay in a supine position may be even better for ensuring optimal comfort, rather than having them sit in a chair during the duration of the treatment, and was done in a few studies for this reason [81,112,126,156,207].…”

Section: Discussionmentioning

confidence: 99%

“…The effect of electrode placement was commonly investigated in these studies, as stimulation of different acupoints may cause very different changes within the cardiovascular system, e.g. stimulation of the hand caused decreased BP and blood flow while stimulation of the tibial and saphenous nerves caused increased BP and blood flow [112,113], although these results may also be attributable to differences in animal and human hemodynamics.…”

Section: Electroacupuncturementioning

confidence: 99%

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Investigating Hemodynamic Responses to Electrical Neurostimulation

Youra¹

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Investigating Hemodynamic Responses to Electrical Neurostimulation Sean YouraSince the 1900s, the number of deaths attributable to cardiovascular disease has steadily risen. With the advent of antihypertensive drugs and non-invasive surgical procedures, such as intravascular stenting, these numbers have begun to level off. Despite this trend, the number of patients diagnosed with some form of cardiovascular disease has only increased. By 2030, prevalence of coronary heart disease is expected to increase approximately by 18% in the United States. By 2050, prevalence of peripheral arterial occlusive disease is expected to increase approximately by 98% in the U.S. No single drug or surgical intervention offers a complete solution to these problems. Thus, a multifaceted regimen of lifestyle changes, medication, and device or surgical interventions is usually necessary. A potential adjunct therapy and cost-effective solution for treating cardiovascular disease that has been overlooked is neurostimulation.Recent studies show that using neurostimulation techniques, such as transcutaneous electrical nerve stimulation (TENS), can help to reduce ischemic pain, lower blood pressure, increase blood flow to the periphery, and decrease systemic vascular resistance. The mechanisms by which these hemodynamic changes occur is still under investigation. The primary aim of this thesis is to elucidate these mechanisms through a thorough synthesis of the existing literature on this subject. Neurostimulation, specifically TENS, is thought to modulate both the metaboreflex and norepinephrine release from sympathetic nerve terminals.To test the hypothesis that TENS increases local blood flow, decreases mean arterial pressure, and decreases cutaneous vascular resistance compared to placebo, in which the electrodes are attached but no electrical stimulation is applied, a protocol was developed to test the effect of neurostimulation on healthy subjects. Implementation of this protocol in a pilot study will determine if neurostimulation causes significant changes in blood flow using the most relevant perfusion measurement instrumentation. Before conducting this study, pre-pilot comparison studies of interferential current therapy (IFC) versus TENS, low frequency (4 Hz) TENS versus high frequency (100 Hz) TENS, and electrode placement on the back versus the forearm were conducted. The only statistically significant difference found was that the application of IFC on the back decreased the reperfusion time, meaning that the time required to reach the average baseline perfusion unit value after occlusion decreased. Further pre-pilot work investigating these different modalities and parameters is necessary to ensure that favorable hemodynamic changes can be detected in the pilot study.

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Depressor effect on blood pressure and flow elicited by electroacupuncture in normal subjects

Cited by 17 publications

References 16 publications

Brain-Modulated Effects of Auricular Acupressure on the Regulation of Autonomic Function in Healthy Volunteers

Brain-Modulated Effects of Auricular Acupressure on the Regulation of Autonomic Function in Healthy Volunteers

The Effects of Thoracic Manipulation on Heart Rate Variability: A Controlled Crossover Trial

Investigating Hemodynamic Responses to Electrical Neurostimulation

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