Der Stickstoffumsatz / Nitrogen Metabolism

Allen, Ethel K.; Allen, O. N.; Böttger, Ilse; Caspersson, T.; Dillemann, Georges; Engel, Horst; Fischer, Hermann O. L.; Guggenheim, M.; Haas, Paul; Haurowitz, Felix; Loomis, W.David; Manshard, Ernst; McKee, H. S.; McQuellen, Kenneth; Mevius, Walter; Moritz, Otto; Mothes, K.; Nielsen, Niels Chr.; Rautanen, Niilo; Romeike, A.; Scheffer, F.; Schmalfuß, K.; Schramm, Gerhard; Schröter, H; Sheat, D. E. G.; Spencer, Donald; Street, H. E.; Stumpf, P.K.; Täufel, K.; Thomas, Meirion; Waldschmidt-Leitz, Ernst; Waley, S. G.; Wilson, P. W.; Yemm, E. W.

doi:10.1007/978-3-642-94733-9

1958

DOI: 10.1007/978-3-642-94733-9

|View full text |Cite

Der Stickstoffumsatz / Nitrogen Metabolism

Ethel K. Allen¹,

O. N. Allen²,

Ilse Böttger³

et al.

Abstract: Alle Rechte, insbesondere das der tJbersetzung in fremde Sprachen, vorbehalten Ohne ausdrlickliche Genehmlgung des Verlages ist es auch nicht gestattet, dleses Buch oder Teile daraus auf photomechanischem Wege (Photokopie, Mikrokopie) zu vervielfiiltigeu © by Springer-Verlag oHG. Berlin• Glittingen• Heidelberg 1958 Softcover reprint of the hardcover 1st edition 1958 Die Wiedergabe von Gebrauchsnamen, Handelsnamen, Warenbezeichnungen usw. in diesem Werk berechtigt auch ohne besondere Kennzeichnung nicht zu der … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Bacterial Proteases as Potentially Exploitable Modulators of SARS-CoV-2 Infection: Logic from the Literature, Informatics, and Inspiration from the Dog

Lushington,

Linde,

Melgarejo

2023

BioTech

View full text Add to dashboard Cite

(1) Background: The COVID-19 pandemic left many intriguing mysteries. Retrospective vulnerability trends tie as strongly to odd demographics as to exposure profiles, genetics, health, or prior medical history. This article documents the importance of nasal microbiome profiles in distinguishing infection rate trends among differentially affected subgroups. (2) Hypothesis: From a detailed literature survey, microbiome profiling experiments, bioinformatics, and molecular simulations, we propose that specific commensal bacterial species in the Pseudomonadales genus confer protection against SARS-CoV-2 infections by expressing proteases that may interfere with the proteolytic priming of the Spike protein. (3) Evidence: Various reports have found elevated Moraxella fractions in the nasal microbiomes of subpopulations with higher resistance to COVID-19 (e.g., adolescents, COVID-19-resistant children, people with strong dietary diversity, and omnivorous canines) and less abundant ones in vulnerable subsets (the elderly, people with narrower diets, carnivorous cats and foxes), along with bioinformatic evidence that Moraxella bacteria express proteases with notable homology to human TMPRSS2. Simulations suggest that these proteases may proteolyze the SARS-CoV-2 spike protein in a manner that interferes with TMPRSS2 priming.

show abstract

Bacterial Proteases as Potentially Exploitable Modulators of SARS-CoV-2 Infection: Logic from the Literature, Informatics, and Inspiration from the Dog

Lushington,

Linde,

Melgarejo

2023

BioTech

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Der Stickstoffumsatz / Nitrogen Metabolism

Cited by 1 publication

References 0 publications

Bacterial Proteases as Potentially Exploitable Modulators of SARS-CoV-2 Infection: Logic from the Literature, Informatics, and Inspiration from the Dog

Bacterial Proteases as Potentially Exploitable Modulators of SARS-CoV-2 Infection: Logic from the Literature, Informatics, and Inspiration from the Dog

Contact Info

Product

Resources

About