Derivative spectrophotometry?recent applications and directions of developments

Karpińska, Joanna

doi:10.1016/j.talanta.2004.03.060

Cited by 149 publications

(84 citation statements)

References 214 publications

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“…According to Karpinska, the main disadvantage of the derivative method is the low reproducibility. 23 Besides, it is necessary have caution with the specificity, mainly for steroidal drugs, with the chemical structures have similar groups that can interfere with the analysis. This point justifies the importance of the development and validation of methods following the principles described by the guidelines.…”

Section: Resultsmentioning

confidence: 99%

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

Mendez¹,

Deconto²,

Garcia³

2010

Quím. Nova

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Recebido em 24/8/09; aceito em 12/11/09; publicado na web em 12/3/10 A derivative UV spectrophotometric method for determination of estradiol valerate in tablets was validated. The parameters specificity, linearity, precision, accuracy, limit of detection and limit of quantitation were studied according to validation guidelines. The first-order derivative spectra were obtained at N = 5, ∆λ = 4.0 nm, and determinations were made at 270 nm. The method showed specificity and linearity in the concentration range of 0.20 to 0.40 mg mL -1. The intra and interday precision data demonstrated the method has good reproducibility. Accuracy was also evaluated and results were satisfactory. The proposed method was successfully applied to a pharmaceutical formulation.

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Section: Resultsmentioning

confidence: 99%

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

Mendez¹,

Deconto²,

Garcia³

2010

Quím. Nova

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“…In this work, the derivative spectrophotometry technique was used, which in this moment is used when the spectral bands are overlapped. On the other hand, different rewiers, about methods that used this technique and its different modalities have been reported [17][18][19][20][21] . On the other hands the past 20 years, various studies show that these drugs represent a new class of environmental contaminants.…”

Section: Introductionmentioning

confidence: 99%

DETERMINATION AND CO-ESTIMATE OF THE CHLORMADINONE ACETATE AND 17α-ETHINYL ESTRADIOL IN PHARMACEUTICAL FORMULATION AND DRINKING WATER SAMPLES BY DIGITAL DERIVATIVE SPECTOPHOTOMETRY

Soto¹,

Otipka

Toral

et al. 2014

J. Chil. Chem. Soc.

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SIn this work are presented two methods for the simultaneous determination of 17α-ethinylestradiol (EEL) and chlormadinone acetate (CMA) by second order derivative spectrophotometry.The first analytical method proposed is based in the dissolution and extraction of both drugs in acetonitrile. The solution was directly evaluated by second order derivative spectrophotometry with a smoothing factor of 8,000 and a scale factor of 10,000. The determination of EEL and CMA was carried out to 296,6 and 291.8 nm, respectively. The detection limits (3.3 σ criterion) for EEL and CMA were 6.9 × 10 -7 and 9.8 × 10 -8 mol / L, respectively. Furthermore, a study of the effect of the excipients containing in the pharmaceutical formulation was included. Polyvidone presents greater tendency to produce interference, but its spectral bands are located between 215 and 240 nm, so these bands do not interferes spectrally in the simultaneous determination of EEL and CMA. Both drugs were extracted from the pharmaceutical formulation with acetonitrile, obtaining a good recovery relative to the nominal content.The second method is a screening method and was applied in fortified drinking water. In this method, drugs were extracted in chloroform, which was then removed with N 2 and the residue was redissolved in acetonitrile. Due to the difference in the procedure in relation to the pharmaceutical formulation a new analytical parameters were obtained. For EEL this parameters were very similar to those obtained directly in solution, however these were higher for CMA, which could be attributed to that under these conditions was found a higher standard deviation of the blank. Recoveries of fortified samples were 81.8 ± 1.5% and 101.1 ± 0.73% for EEL and CMA, respectively.

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“…Several spectrophotometric methods, such as derivative spectrophotometry, [1][2][3][4][5] ratio spectra derivative method, 6 ratio spectra derivative-zero crossing method, 7-9 DDRS-DS method [10][11][12][13][14] and double divisor-ratio spectra derivative-zero crossing method 15 have been reported in the literature and applied for ternary and quaternary mixtures. However, it was observed that the derivative spectrophotometry and ratio spectra derivative method provide a good analytical resolution of binary mixtures but these two methods do not give always desirable results for the analysis of ternary and quaternary mixtures.…”

Section: Introductionmentioning

confidence: 99%

Application of Haar and Mexican hat wavelets to double divisor-ratio spectra for the multicomponent determination of ascorbic acid, acetylsalicylic acid and paracetamol in effervescent tablets

Dinç¹,

Băleanu²

2008

J. Braz. Chem. Soc.

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A determinação simultânea de ácido ascórbico (AA), ácido acetilsalicílico (ASP) e paracetamol (PAR) em misturas sintéticas e tabletes efervescentes foi realizada usando-se as técnicas de transformações de Haar e transformações de onda pequena tipo chapéu mexicano (HAAR-CWT e MEXH-CWT, respectivamente), juntamente com a técnica de divisor duplo. Os métodos de processamento de sinal são baseados na aplicação de HAAR-CWT e MEXH-CWT aos espectros relativos com divisor duplo (DDRS). Estes espectros foram obtidos pela divisão do espectro de absorção do composto puro e suas misturas ternárias, por um divisor duplo ou espectro padrão correspondente à mistura de dois compostos em mistura ternária. O uso combinado de HAAR-CWT e MEXH-CWT com espectros relativos com divisor duplo (DDRS) foi denominado DDRS-HAAR CWT e DDRS-MEXH CWT. Para avaliar a habilidade ou aplicabilidade dos métodos desenvolvidos DDRS-CWT, foi aplicado como comparação, o método espectrofotométrico por derivada de espectros relativos com divisor duplo (DDRS-DS), às amostras mencionadas acima, contendo AA, ASP e PAR. Resultados satisfatórios foram obtidos.Simultaneous determination of ascorbic acid (AA), acetylsalicylic acid (ASP) and paracetamol (PAR) in their synthetic mixtures and effervescent tablets were performed by Haar and Mexican continuous wavelet transforms (HAAR-CWT and MEXH-CWT, respectively) together with double divisor technique. The signal processing methods are based on the application of HAAR-CWT and MEXH-CWT to the double divisor-ratio spectra (DDRS). These spectra were obtained by dividing the absorption spectra of pure compound and its ternary mixtures by a double-divisor or standard spectrum corresponding to a mixture of two compounds in ternary mixture. A combined use of HAAR-CWT and MEXH-CWT with double divisor-ratio spectra (DDRS) was denoted by DDRS-HAAR CWT and DDRS-MEXH CWT. To check the ability or applicability of the developed DDRS-CWT methods, the double divisor-ratio spectra-derivative spectrophotometric (DDRS-DS) method, as a comparison method, was applied to the above mentioned samples containing AA, ASP and PAR and satisfactory results were obtained.

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Derivative spectrophotometry?recent applications and directions of developments

Cited by 149 publications

References 214 publications

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

DETERMINATION AND CO-ESTIMATE OF THE CHLORMADINONE ACETATE AND 17α-ETHINYL ESTRADIOL IN PHARMACEUTICAL FORMULATION AND DRINKING WATER SAMPLES BY DIGITAL DERIVATIVE SPECTOPHOTOMETRY

Application of Haar and Mexican hat wavelets to double divisor-ratio spectra for the multicomponent determination of ascorbic acid, acetylsalicylic acid and paracetamol in effervescent tablets

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Derivative spectrophotometry?recent applications and directions of developments

Cited by 149 publications

References 214 publications

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

DETERMINATION AND CO-ESTIMATE OF THE CHLORMADINONE ACETATE AND 17&#945;-ETHINYL ESTRADIOL IN PHARMACEUTICAL FORMULATION AND DRINKING WATER SAMPLES BY DIGITAL DERIVATIVE SPECTOPHOTOMETRY

Application of Haar and Mexican hat wavelets to double divisor-ratio spectra for the multicomponent determination of ascorbic acid, acetylsalicylic acid and paracetamol in effervescent tablets

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DETERMINATION AND CO-ESTIMATE OF THE CHLORMADINONE ACETATE AND 17α-ETHINYL ESTRADIOL IN PHARMACEUTICAL FORMULATION AND DRINKING WATER SAMPLES BY DIGITAL DERIVATIVE SPECTOPHOTOMETRY