Dermal Matrix for Intraoral Lining Following Composite Mandibular Defect Reconstruction With Chimeric Fibular Osseocutaneous Flap

Gravvanis, Andreas; Kakagia, Despoina; Katsikeris, Nick; Tsoutsos, Dimosthenis

doi:10.1097/scs.0000000000002930

Cited by 4 publications

(8 citation statements)

References 28 publications

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“…19-21 Furthermore, artificial dermis has been effectively used to reinforce free flaps used for sole and heel reconstruction 22 and are considered to be useful adjuncts in free flap reconstruction of complex defects. 19,22…”

Section: Discussionmentioning

confidence: 99%

“…Dermal matrices have been reported to effectively cover skin deficits resulting not only from burns, 16 but also from chronic wounds including venous and diabetic ulcers, 17 any trauma, 18 and after tumor excision. [19][20][21] Furthermore, artificial dermis has been effectively used to reinforce free flaps used for sole and heel reconstruction 22 and are considered to be useful adjuncts in free flap reconstruction of complex defects. 19,22 Dermal matrices, consisting of acellular collagen and elastin fibers, cover the wound and act as scaffolds to guide the migration and proliferation of autologous fibroblasts to the wound bed.…”

Section: Discussionmentioning

confidence: 99%

“…Although costly, they have been documented to offer a reliable scaffold for dermal regeneration and a durable resurfacing option preventing adhesions and dehiscence. 16-20…”

Section: Introductionmentioning

confidence: 99%

“…Although costly, they have been documented to offer a reliable scaffold for dermal regeneration and a durable resurfacing option preventing adhesions and dehiscence. [16][17][18][19][20] The present article aims to present the use of dermal matrices in severe degloving, avulsion, and necrotizing injuries of the leg and foot in 3 patients. All patients were eventually managed with extensive surgical debridement followed by NPWT, and reconstructed with artificial dermis and autologous skin grafting.…”

Section: Introductionmentioning

confidence: 99%

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Dermal Matrices: Game Changers in Leg and Foot Soft Tissue Reconstruction? A Case Series

Kakagia

Georgiadis

Drosos

2021

The International Journal of Lower Extremity Wounds

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The present article aims to present the use of dermal matrices in severe degloving, avulsion, and necrotizing injuries of the leg and foot in 3 patients. Conventional reconstruction would require the use of free flaps, since exposure of vessels, nerves, joints, and tendons rendered the mere resurfacing with skin grafts insufficient, and extensive cutaneous detachment precluded the use of local fasciocutaneous flaps. All injuries underwent thorough and repeated surgical debridements and wash outs, followed by negative pressure wound therapy (NPWT). Once negative tissue cultures were obtained, the extremities were resurfaced with dermal matrix and immediately covered by split thickness skin grafts. NPWT on the grafted area for a week effectively secured the grafts on the recipient area. Complete healing was achieved in all grafted areas within 7 to 12 days. The function of joints and tendons as well as the quality of resurfacing at the weight bearing areas were tested and found satisfactory within a follow-up period of 5 to 15 months. The use of combined NPWT and dermal matrices in carefully selected patients provides a reliable and durable reconstructive option for leg and foot injuries with satisfactory functional outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Although costly, they have been documented to offer a reliable scaffold for dermal regeneration and a durable resurfacing option preventing adhesions and dehiscence. 16-20…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dermal Matrices: Game Changers in Leg and Foot Soft Tissue Reconstruction? A Case Series

Kakagia

Georgiadis

Drosos

2021

The International Journal of Lower Extremity Wounds

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“…The Integra was noted to have 100% take at removal of the silicone layer at 2 weeks, with subsequent spontaneous mucosalization that was sufficiently robust to support dental implants. 26…”

Section: Head and Neckmentioning

confidence: 99%

The Basics of Integra Dermal Regeneration Template and its Expanding Clinical Applications

Chang

Louis

Giménez

et al. 2019

Seminars in Plastic Surgery

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First developed for coverage of burn wounds, Integra (Integra LifeSciences) is a synthetic acellular dermal regeneration template that provides a base for revascularization and neodermal formation. The use of Integra has slowly grown and has now become an important consideration along the reconstructive ladder. This article reviews the basic science of Integra and provides an overview of the many expanding applications based on anatomic location.

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Dermal Regeneration Template: Reconstruction in Oral Cancer Defects

Mangini

Galvano

Pucci

et al. 2023

J. Maxillofac. Oral Surg.

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Background Post ablative oral mucosal defect resulting from the removal of tumors can be treated with various techniques. Purpose In this paper, we are showing what, in our experience, are the advantages and disadvantages given using biosynthetic skin substitutes when dealing with this kind of lesions. Materials and methods Patients included in the sample came to our attention with both neoplastic lesions (11 subjects) and important scar retraction after previous oncologic surgery (1 subject). All patients underwent trans-oral resection surgery following the same surgical protocol and post ablative oral mucosal defect were treated using the dermal regeneration template. The surgical defect location, size, and time of removal of the silicone layer varied from one subject to the other. Results Most patients showed good healing with reduced scarring and adequate remucosalisation of the defect. The main complications were shown in a palatal lesion treated with concomitant osteal resection, which developed an oroantral fistula at follow up, and tongue lesions which showed some scarring. Conclusions Given our experience, we would advise using dermal substitutes when reconstructing oral defects only after a cautious evaluation of the area of the lesion, the gap size, the possible adherence of the membrane to the gap, and the presence of tissue supporting the overlying membrane.

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Dermal Matrix for Intraoral Lining Following Composite Mandibular Defect Reconstruction With Chimeric Fibular Osseocutaneous Flap

Abstract: Integra was safely used as an alternative for intraoral lining, in composite mandibular reconstruction, downgrading reconstructive demands and offering optimal functional results.

Cited by 4 publications

References 28 publications

Dermal Matrices: Game Changers in Leg and Foot Soft Tissue Reconstruction? A Case Series

Dermal Matrices: Game Changers in Leg and Foot Soft Tissue Reconstruction? A Case Series

The Basics of Integra Dermal Regeneration Template and its Expanding Clinical Applications

Dermal Regeneration Template: Reconstruction in Oral Cancer Defects

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