Dermal tolerance and effect on skin hydration of a new ethanol-based hand gel

Transdermal absorption of ethanol- and 1-propanol-containing hand disinfectants

“…The lack of some of the above measures could explain the higher serum blood alcohol levels reported in other studies [5,10,11]. The results of this study also showed that the study formulations were well tolerated and did not demonstrate any clinically relevant potential for dermal irritation, which is similar to other studies testing the dermal tolerance of alcohol-based hand disinfectants [21,22]. A limitation of this study is that in the real world of hand hygiene, healthcare workers perform hand hygiene more than once a day with many different alcohol formulations.…”

Alcohol-based hand disinfection: a more robust hand-hygiene method in an intensive care unit

“…24,25,27 Many HCWs are bothered with sore and dry skin on their hands, and several studies have shown that hand disinfection leaves the skin less irritated and sore than handwashing. 17,25,[28][29][30] Skin problems are reported as discouraging for hand hygiene among HCWs, so this advantage of hand disinfection is important. It is described that advantages like this motivate HCWs in this important function.…”

Surgical hand disinfection with a propanol-based hand rub: equivalence of shorter application times

“…7 Alcohol-based hand rubs are often preferred to antimicrobial soaps based on chlorhexidine or PVP iodine because they have a broader spectrum of activity, [8][9][10][11] act faster [11][12][13] and have a better skin tolerance. 11,[14][15][16][17] The clinical impact on the incidence of surgical-site infections, however, is not clear. 14 The history of surgical hand disinfection underwent a few changes in the last century.…”