Derrame pleural tipo trasudado como expresión de afectación pleural por amiloidosis

Pérez-Rodríguez, M. Teresa; Vázquez, C. Martínez; Villarroel, Paula González; Pérez-Argüelles, Bernardo Sopeña; Villar, Alberto Fernández

doi:10.1157/13111559

Cited by 2 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PE was bilateral in 59/107 patients (55%), right sided in 36 (34%)[ 8 9 11 14 17 20 22 27 29 32 33 34 37 41 42 43 45 48 51 55 56 65 67 76 79 83 86 88 91 94 99 101 ] and left sided in 12 (11%). [ 13 23 24 30 35 38 46 60 69 81 97 ] PE was not identified as unilateral or bilateral in 89 cases (45%). The size of PE was documented in 92 cases (47%).…”

Section: Resultsmentioning

confidence: 99%

“…A total of 95 articles published over a period of 63 years were included, representing a final sample of 196 patients with PA. Figure 1 shows the flow chart of the article selection process. [ 8 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 <...…”

Section: Resultsmentioning

confidence: 99%

“…Only nine cases[ 10 30 35 77 78 82 83 90 94 ] (4.6%) met the diagnostic criteria for primary amyloidosis (plasma cell proliferation, organ damage related to amyloidosis, positive Congo Red amyloid staining in some tissue, and evidence of amyloid light chain on electron microscopy). [ 10 ] Pleural biopsy was performed in 67 patient [(28 by closed pleural biopsy[ 18 30 33 34 38 39 41 42 45 47 49 55 60 61 88 ] and 30 by pleuroscopy (medical or surgical)[ 8 9 10 20 29 30 37 41 51 55 62 65 72 73 75 76 78 79 81 83 84 87 88 90 92 93 97 99 ], in 9 cases the type of biopsy was not detailed. [ 14 22 23 24 67 70 74 96 98 ]] Amyloid PE was confirmed in 56 patient [21 by closed pleural biopsy[ 18 30 33 34 42 45 47 49 60 61 ] and 29 by pleuroscopy;[ 8 …”

Section: Resultsmentioning

confidence: 99%

“…[ 10 ] Pleural biopsy was performed in 67 patient [(28 by closed pleural biopsy[ 18 30 33 34 38 39 41 42 45 47 49 55 60 61 88 ] and 30 by pleuroscopy (medical or surgical)[ 8 9 10 20 29 30 37 41 51 55 62 65 72 73 75 76 78 79 81 83 84 87 88 90 92 93 97 99 ], in 9 cases the type of biopsy was not detailed. [ 14 22 23 24 67 70 74 96 98 ]] Amyloid PE was confirmed in 56 patient [21 by closed pleural biopsy[ 18 30 33 34 42 45 47 49 60 61 ] and 29 by pleuroscopy;[ 8 9 10 20 29 30 37 41 51 55 62 65 72 73 75 76 ...…”

Section: Resultsmentioning

confidence: 99%

“…Response to treatment was defined as the total or partial control of PE or its symptoms. Only 31 (12.4%) patients showed good response to treatment (6 with the first treatment administered,[ 15 20 32 44 54 83 ] 14 with the second,[ 8 11 38 43 46 58 59 60 77 79 80 84 86 96 ] 6 with the third[ 10 47 51 63 78 ] and 5 with the fourth treatment administered[ 28 40 48 66 67 ]). Table 4 details the most frequent treatments or procedures (used in at least five cases).…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Characteristics of pleural effusion due to amyloidosis

Ferreiro¹,

Pou²,

Suárez-Antelo³

et al. 2023

Annals of Thoracic Medicine

View full text Add to dashboard Cite

The characteristics of patients with pleural amyloidosis (PA) are poorly known. A systematic review was performed of studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of PA. Case descriptions and retrospective studies were included. The review included 95 studies with a total sample of 196 patients. The mean age was 63 years, male/female ratio was 1.6:1, and 91.9% of patients were >50 years. The most common symptom was dyspnea (88 patients). PF was generally serious (63%), predominantly lymphocytic, and with the biochemical characteristics of transudates (43.4%) or exudates (42.6%). Pleural effusion was generally bilateral (55%) and <1/3 of the hemithorax (50%), although in 21% pleural effusion (PE) exceeded 2/3. Pleural biopsy was performed in 67 patients (yield: 83.6%; 56/67) and was positive in 54% of exudates and 62.5% of unilateral effusions. Of the 251 treatments prescribed, only 31 were effective (12.4%). The combination of chemotherapy and corticosteroids was effective in 29.6% of cases, whereas talc pleurodesis was effective in 21.4% and indwelling pleural catheter in 75% of patients (only four patients). PA is more frequent in adults from 50 years of age. PF is usually bilateral, serous, and indistinctly a transudate or exudate. A pleural biopsy can aid in diagnosis if effusion is unilateral or an exudate. Treatments are rarely effective and there may be definitive therapeutic options for PE in these patients.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Characteristics of pleural effusion due to amyloidosis

Ferreiro¹,

Pou²,

Suárez-Antelo³

et al. 2023

Annals of Thoracic Medicine

View full text Add to dashboard Cite

show abstract

Primary systemic amyloidosis and persistent pleural effusions

Schwarz¹,

Jue

Sikov

2009

Amyloid

View full text Add to dashboard Cite

Persistent pleural effusions are not common in patients with primary systemic amyloidosis (AL). A recent review of this complication of the disease hypothesized that the pathophysiology of these effusions is pleural amyloid deposition, disrupting lymphatic drainage. We report the case of a 73-year-old woman with primary systemic AL and persistent bilateral pleural effusions, refractory to diuresis and repeated thoracenteses. The patient's cardiac and renal dysfunction was not severe enough to explain these persistent effusions. Thus, despite a lack of biopsy-proven amyloid deposition, we suggest that these effusions may be secondary to pleural amyloid deposition.

show abstract

Derrame pleural tipo trasudado como expresión de afectación pleural por amiloidosis

Cited by 2 publications

References 8 publications

Characteristics of pleural effusion due to amyloidosis

Characteristics of pleural effusion due to amyloidosis

Primary systemic amyloidosis and persistent pleural effusions

Contact Info

Product

Resources

About