“…42 Instead, because health disparities are downstream outcomes of upstream inequities, addressing upstream structural determinants of health and SDoH is essential. Although Ashenafi et al 43 do not mention health equity approaches in their title, they advocate strategic reduction in disparities in COVID-19 immunization uptake through health equity principles, such as those described by Burton et al 44 Their study demonstrates the essential components of applying equity principles of interest holder analysis, engagement, and collaboration when designing federal programs to reduce disparities in adult COVID-19 immunization uptake. The case study shows that to achieve health equity, interventions should empower people through progress in equitable access to SDoH.…”