Design and Implementation of Comprehensive Gas Chromatography with Cryogenic Modulation

La cromatografía de gases acoplada a espectrometría de masas como herramienta de alta selectividad para caracterizar fósiles químicos en el petróleo

“…4 El aumento de la resolución cromatográfica con la cromatografía completa, GC x GC El flujo de la primera columna es fraccionado en múltiples segmentos, que se transfieren consecutivamente a la segunda columna (cromatografía rápida), que está conectada a un detector de alta velocidad de respuesta, normalmente, un espectrómetro de masas con analizador de tiempo de vuelo (MS-TOF) [21] . El resultado es un perfil cromatográfico bidimensional cuyos ejes son los tiempos de retención en cada columna.…”

Observation of non-linear chromatographic peaks in comprehensive two-dimensional gas chromatography

“…The GC6GC experiment is achieved here by use of a cryogenic modulator as described elsewhere [9]; the pneumatic system outlined therein is replaced with a motor drive in the present model. The first demonstration of the principles of rapid longitudinal cryogenic modulation was described in 1997 [10], and a summary of its unique capabilities recently reported [11].…”

“…The CO 2 cryogen coolant maintains the temperature of the modulation trap to at least 1008C below the prevailing oven temperature. Reference [9] should be consulted for details of the instrument setup.…”

Valve-based comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection: instrumentation and figures-of-merit

“…Most GC × GC instruments employ thermal modulation [32][33][34][35][36][37][38][39], but there are a growing number of valve-based GC × GC instruments [5,16,[40][41][42][43]. One recent advance in valve-based GC × GC instrumentation was adaptation of a new valve-placement that extends the working temperature range of valve-based instruments to ∼250 • C, which is 75 • C above the manufacturer's specified temperature limit of the valve [43].…”