Security threat is a crucial issue in cognitive radio network (CRN). These threats come from physical layer, data link layer, network layer, transport layer, and application layer. Hence, security system to all layers in CRN has a responsibility to protect the communication between among Secondary User (SU) or to maintain valid detection to the presence of Primary User (PU) signals. Primary User Emulation Attack (PUEA) is a threat on physical layer where malicious user emulates PU signal. This paper studies the effect of exclusive region of PUEA in CRN. We take two setting of exclusive distances, 30m and 50m, where this radius of area is free of malicious users. Probability of false alarm (Pf) and miss detection (Pm) are used to evaluate the performances. The result shows that increasing distance of exclusive region may decrease Pf and Pm.