Design, synthesis, and biological evaluation of morpholinopyrimidine derivatives as anti-inflammatory agents

Abstract

Here, we outline the synthesis of a few 2-methoxy-6-((4-(6-morpholinopyrimidin-4-yl)piperazin-1-yl)(phenyl)methyl)phenol derivatives and assess their anti-inflammatory activity in macrophage cells that have been stimulated by LPS.