Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors

Maccari, Rosanna; Wolber, Gerhard; Genovese, Massimo; Sardelli, Gemma; Talagayev, Valerij; Balestri, Francesco; Luti, Simone; Santi, Alice; Moschini, Roberta; Corso, Antonella Del; Paoli, Paolo De; Ottanà, Rosaria

doi:10.2139/ssrn.4345262

2023

DOI: 10.2139/ssrn.4345262

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Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors

Rosanna Maccari

Gerhard Wolber

Massimo Genovese

et al.

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Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors

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References 51 publications

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