Designing and prototyping a novel biosensor based on a volumetric bar-chart chip for urea detection

Samadi Khezri, Mahdi; Housaindokht, Mohammad Reza; Firouzi, Mojtaba

doi:10.1039/d3lc00730h

Lab Chip

2024

DOI: 10.1039/d3lc00730h

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Designing and prototyping a novel biosensor based on a volumetric bar-chart chip for urea detection

Mahdi Samadi Khezri,

Mohammad Reza Housaindokht,

Mojtaba Firouzi

Abstract: A volumetric bar-chart chip (V-chip) is a microfluidic device based on distance-based quantitative measurement that visualizes analyte concentration without the need for apparatus or data processing.

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Overview of Gas-Generating-Reaction-Based Immunoassays

Yu,

Deng,

Liang

et al. 2024

Biosensors

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Point-of-care (POC) immunoassays have become convincing alternatives to traditional immunosensing methods for the sensitive and real-time detection of targets. Immunoassays based on gas-generating reactions were recently developed and have been used in various fields due to their advantages, such as rapid measurement, direct reading, simple operation, and low cost. Enzymes or nanoparticles modified with antibodies can effectively catalyze gas-generating reactions and convert immunorecognition events into gas pressure signals, which can be easily recorded by multifunctional portable devices. This article summarizes the advances in gas-generating-reaction-based immunoassays, according to different types of signal output systems, including distance-based readout, pressure differential, visualized detection, and thermal measurement. The review mainly focuses on the role of photothermal materials and the working principle of immunoassays. In addition, the challenges and prospects for the future development of gas-generating-reaction-based immunoassays are briefly discussed.

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Overview of Gas-Generating-Reaction-Based Immunoassays

Yu,

Deng,

Liang

et al. 2024

Biosensors

View full text Add to dashboard Cite

show abstract

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Designing and prototyping a novel biosensor based on a volumetric bar-chart chip for urea detection

Abstract: A volumetric bar-chart chip (V-chip) is a microfluidic device based on distance-based quantitative measurement that visualizes analyte concentration without the need for apparatus or data processing.

Cited by 1 publication

References 38 publications

Overview of Gas-Generating-Reaction-Based Immunoassays

Overview of Gas-Generating-Reaction-Based Immunoassays

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